Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	117681
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Evidence-Based Medicine
Article Title	Advantages of low dose polyethylene glycol + ascorbate split-dose colonoscopy preparation for colorectal screening
Manuscript Source	Unsolicited Manuscript
All Author List	Caterina Palmonari, Nicolò Landini, Chiara Zanforlin, Michela Borghesi, Viviana Cifalà, Claudio Gregorio, Alessandro Pezzoli, Admena Rreshketa and Chiara Chiericati
Funding Agency and Grant Number
Corresponding Author	Nicolò Landini, Post Doctoral Researcher, AUSL-U.O.C. Oncological Screenings, Local Health Agency of Ferrara, Corso Della Giovecca 203, Ferrara 44121, Emilia-Romagna, Italy. nicolo.landini@unife.it
Key Words	Colorectal cancer; Colonoscopy preparation; Polyethylene glycol; Diagnostics; Colonoscopy; Preventive medicine; Oncological screening; Oncology; Drugs implementation; Medical protocols
Core Tip	The 1-liter of polyethylene glycol and ascorbate was introduced to enhance colonoscopy preparation from the standard (4-liter of polyethylene glycol, distressful for patients due to the volume and not operatively optimal due to poor bowel cleansing). Results from pilot study (426 patients) showed above 90% of the patients with adequate bowel cleansing (Boston Scale value ≥ 6). Provincial screening results from 2022 to 2023 after the renewed protocol resulted in 96.33% of the population having adequate bowel cleansing for colonoscopy, with 63.56% showing optimal cleaning. Patients’ compliance increased of +5.30% for 1st and +3.90% for 2nd level screening protocols.
Citation	Palmonari C, Landini N, Zanforlin C, Borghesi M, Cifalà V, Gregorio C, Pezzoli A, Rreshketa A, Chiericati C. Advantages of low dose polyethylene glycol + ascorbate split-dose colonoscopy preparation for colorectal screening. World J Gastrointest Oncol 2026; In press

Received	2025-12-15 02:32
Peer-Review Started	2025-12-15 02:32
First Decision by Editorial Office Director	2026-01-20 09:27
Return for Revision	2026-01-21 13:39
Revised	2026-02-03 17:48
Publication Fee Transferred	2026-02-10 10:28
Second Decision by Editor	2026-04-14 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-14 08:20
Articles in Press	2026-04-14 08:20
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com