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Publication Name World Journal of Gastroenterology
Manuscript ID 117785
Country Australia
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Hepatocellular carcinoma in patients without cirrhosis: Urgent need to include Australasian populations
Manuscript Source Unsolicited Manuscript
All Author List Aparna Morgan, Angela Zhu, Nicholas Hannah, James Haridy, Ashok Raj and Neeraj Bhala
Funding Agency and Grant Number
Corresponding Author Neeraj Bhala, Consultant, Director, FRACP, FRCP, FRCPE, Head, PhD, Professor, Department of Gastroenterology and Hepatology, Royal Melbourne Hospital & The University of Melbourne, 300 Grattan St, Parkville VIC 3050, Melbourne 3050, Victoria, Australia. neeraj.bhala@mh.org.au
Key Words Hepatocellular carcinoma; Non-cirrhotic; Metabolic dysfunction-associated steatotic liver disease; Hepatitis B; Hepatitis C; Australasia; Aboriginal and Torres Strait Islander people; Māori and Pasifika people
Core Tip Global reviews of hepatocellular carcinoma (HCC) that exclude Australasian data risk overlooking important epidemiological patterns. In Australia and New Zealand, non-cirrhotic HCC accounts for a substantial proportion of cases, driven predominantly by chronic hepatitis B and an increasing burden of metabolic dysfunction-associated steatotic liver disease, particularly among Indigenous and migrant populations. Inclusion of Australasian data is essential for a truly comprehensive understanding of non-cirrhotic HCC risk and surveillance worldwide.
Citation Morgan A, Zhu A, Hannah N, Haridy J, Raj A, Bhala N. Hepatocellular carcinoma in patients without cirrhosis: Urgent need to include Australasian populations. World J Gastroenterol 2026; In press
Received
2025-12-17 02:22
Peer-Review Started
2025-12-17 02:23
First Decision by Editorial Office Director
2026-01-07 10:19
Return for Revision
2026-01-07 10:19
Revised
2026-01-20 09:24
Publication Fee Transferred
Second Decision by Editor
2026-01-29 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-29 06:50
Articles in Press
2026-01-29 06:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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