Publication Name	World Journal of Gastroenterology
Manuscript ID	117799
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Plasma proteomic profiling of gastric cancer: Super minimally invasive surgery vs organ-resection on trauma immunity
Manuscript Source	Unsolicited Manuscript
All Author List	Yao-Qian Yuan, Qian-Qian Chen, Pan Xiao, Hui-Kai Li, Kun-Ming Lv, Shuai Tian, Hui Shi, Jing Hao, Yang Yan and En-Qiang Linghu
Funding Agency and Grant Number	Funding Agency Grant Number National Key Research and Development Program of China 2022YFC2503601
Corresponding Author	En-Qiang Linghu, Associate Chief Physician, Associate Professor, Chief Physician, Director, MD, Professor, Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, Fuxing Road 28, Haidian District, Beijing 100853, China. linghuenqiang@vip.sina.com
Key Words	Gastric cancer; Organ-resection surgery; Super minimally invasive surgery; Trauma immunity; Inflammatory response
Core Tip	The optimal extent of surgical intervention for gastric cancer remains controversial, particularly with respect to its impact on postoperative immune homeostasis. This study integrates super minimally invasive surgery concepts with proteomic profiling to investigate immune-inflammatory alterations following different surgical strategies, providing mechanistic insights that may support more individualized, trauma-conscious surgical decision-making in early gastric cancer.
Citation	Yuan YQ, Chen QQ, Xiao P, Li HK, Lv KM, Tian S, Shi H, Hao J, Yan Y, Linghu EQ. Plasma proteomic profiling of gastric cancer: Super minimally invasive surgery vs organ-resection on trauma immunity. World J Gastroenterol 2026; In press

Received	2025-12-16 08:45
Peer-Review Started	2025-12-16 08:45
First Decision by Editorial Office Director	2026-01-06 07:18
Return for Revision	2026-01-06 07:18
Revised	2026-01-18 12:52
Publication Fee Transferred	2026-01-19 03:43
Second Decision by Editor	2026-02-12 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-12 08:45
Articles in Press	2026-02-12 08:45
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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