Publication Name	World Journal of Cardiology
Manuscript ID	117800
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Letter to the Editor
Article Title	Culprit coronary occlusion as a stronger short-term prognostic marker over electrocardiographic pattern in acute myocardial infarction
Manuscript Source	Invited Manuscript
All Author List	Sahiljeet Singh and Neiberg de Alcantara Lima
Funding Agency and Grant Number
Corresponding Author	Neiberg de Alcantara Lima, FACC, FACP, MD, Division of Cardiology, Hartford HealthCare Heart and Vascular Institute, Hartford Hospital, 85 Jefferson Street, Hartford, CT 06106, United States. neiberglima@me.com
Key Words	Infarct-related artery occlusion; Electrocardiographic presentation; Acute myocardial infarction; Troponin; Statin therapy
Core Tip	This letter discusses the study by Kos et al and emphasizes that in acute myocardial infarction, the presence of a totally occluded culprit artery drives short-term mortality risk more than the electrocardiogram classification (ST- segment elevation vs non-ST segment elevation). We also note troponin as a practical, but imperfect, surrogate for infarct size and urge cautious interpretation. Finally, the association between previous statin use and a lower likelihood of presentation with total occlusion suggests plaque stabilizing effects of statins that merit further investigation.
Citation	Singh S, Lima NDA. Culprit coronary occlusion as a stronger short-term prognostic marker over electrocardiographic pattern in acute myocardial infarction. World J Cardiol 2026; In press

Received	2025-12-16 01:05
Peer-Review Started	2025-12-16 01:08
First Decision by Editorial Office Director	2025-12-26 10:26
Return for Revision	2025-12-26 10:26
Revised	2025-12-29 00:43
Publication Fee Transferred
Second Decision by Editor	2026-02-13 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-13 03:59
Articles in Press	2026-02-13 03:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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