Publication Name	World Journal of Clinical Cases
Manuscript ID	117846
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Atherogenic index of plasma in stroke: A comprehensive review of its diagnostic, prognostic, and pathophysiological significance
Manuscript Source	Invited Manuscript
All Author List	Hemanth Dhananjaya, Himanshu S Jog, Shashank Gupta, Arankesh Mahadevan, Shaylika Chauhan and Rupak Desai
Funding Agency and Grant Number
Corresponding Author	Shaylika Chauhan, FACP, FRCP, MD, Department of Internal Medicine, Geisinger Health System, 1000 E Mountain Blvd, Wikes-Barre, PA 18711, United States. drshaylikachauhan@gmail.com
Key Words	Atherogenic index of plasma; Ischemic stroke; Intracranial atherosclerosis; Early neurological deterioration; Insulin resistance; Biomarker
Core Tip	The atherogenic index of plasma (AIP), calculated as the logarithmic ratio of triglycerides to high-density lipoprotein cholesterol, is an emerging cardiometabolic biomarker that integrates dyslipidemia and insulin resistance. This review highlights consistent evidence linking elevated AIP with increased ischemic stroke risk, greater stroke severity, early neurological deterioration, and poorer outcomes, particularly in individuals with diabetes and metabolic syndrome. By reflecting endothelial dysfunction, vascular inflammation, and atherosclerotic burden, AIP offers a low-cost, readily available tool with potential to enhance stroke risk stratification and preventive cardiometabolic care.
Citation	Dhananjaya H, Jog HS, Gupta S, Mahadevan A, Chauhan S, Desai R. Atherogenic index of plasma in stroke: A comprehensive review of its diagnostic, prognostic, and pathophysiological significance. World J Clin Cases 2026; In press

Received	2025-12-23 06:31
Peer-Review Started	2025-12-23 06:31
First Decision by Editorial Office Director	2025-12-31 07:53
Return for Revision	2025-12-31 07:53
Revised	2026-01-12 10:04
Publication Fee Transferred
Second Decision by Editor	2026-02-04 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-04 07:08
Articles in Press	2026-02-04 07:08
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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