Publication Name	World Journal of Experimental Medicine
Manuscript ID	117853
Country	Egypt

Category	Medicine, General & Internal
Manuscript Type	Case Control Study
Article Title	Evaluation of growth hormone provocative tests in Egyptian children with growth hormone-related short stature
Manuscript Source	Invited Manuscript
All Author List	Ahmed El-Abd Ahmed, Mohammed H Hassan, Renada Saad Hamdan and Hala M Sakhr
Funding Agency and Grant Number
Corresponding Author	Mohammed H Hassan, MD, Professor, Department of Medical Biochemistry and Molecular Biology, Qena University, Qena 83523, Egypt. mohammedhosnyhassaan@yahoo.com
Key Words	Short stature; Growth hormone; Provocative tests; Children; Insulin-induced peak
Core Tip	Growth hormone provocative testing in children demonstrates considerable variability, which can complicate the accurate diagnosis of GH deficiency. This study emphasizes that oral clonidine and levodopa stimulation tests represent safer, more practical, and reliable alternatives to the insulin tolerance test. Additionally, adopting lower, optimized cut-off values for GH levels enhances diagnostic precision and reduces the risk of misclassification in pediatric patients undergoing evaluation.
Citation	Ahmed AEA, Hassan MH, Hamdan RS, Sakhr HM. Evaluation of growth hormone provocative tests in Egyptian children with growth hormone-related short stature. World J Exp Med 2026; In press

Received	2025-12-18 01:52
Peer-Review Started	2025-12-18 01:53
First Decision by Editorial Office Director	2026-02-04 09:47
Return for Revision	2026-02-04 09:47
Revised	2026-03-13 09:14
Publication Fee Transferred
Second Decision by Editor	2026-04-13 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-13 07:10
Articles in Press	2026-04-13 07:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-315x (online)
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