Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	117856
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Randomized Controlled Trial
Article Title	Synergistic effect of Codonopsis lanceolata and clip-line traction in endoscopic submucosal dissection for early esophageal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Dai Shi and Liang Zheng
Funding Agency and Grant Number
Corresponding Author	Liang Zheng, Chief Physician, Department of Gastroenterology, The Second Affiliated Hospital of Nanjing University of Chinese Medicine, No. 23 Nanhu Road, Jiandu District, Nanjing 210000, Jiangsu Province, China. sd479324634@163.com
Key Words	Taishan Codonopsis; Early esophageal cancer; Clipping wire traction; Endoscopic submucosal dissection; C-reactive protein
Core Tip	This randomized trial demonstrates that the perioperative administration of Taishan Codonopsis (Codonopsis lanceolata) combined with clipping wire traction-assisted endoscopic submucosal dissection offers significant clinical benefits for early esophageal cancer. This integrative strategy effectively attenuates systemic inflammation (reduced C-reactive protein), mitigates postoperative pain, expedites functional recovery, shortens hospital stay, enhances ulcer healing, and lowers complication rates, providing an effective and safe adjunct to modern endoscopic therapy.
Citation	Shi D, Zheng L. Synergistic effect of Codonopsis lanceolata and clip-line traction in endoscopic submucosal dissection for early esophageal cancer. World J Gastrointest Surg 2026; In press

Received	2026-01-20 09:56
Peer-Review Started	2026-01-20 09:56
First Decision by Editorial Office Director	2026-01-30 08:52
Return for Revision	2026-01-30 08:52
Revised	2026-02-06 07:17
Publication Fee Transferred
Second Decision by Editor	2026-03-10 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-10 05:51
Articles in Press	2026-03-10 05:51
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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