Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	117885
Country	Italy

Category	Pediatrics
Manuscript Type	Retrospective Cohort Study
Article Title	Neonatal chylothorax and ultrasound: Diagnosis, measurements, and correlations with management
Manuscript Source	Invited Manuscript
All Author List	Alessandro Perri, Annamaria Sbordone, Simona Fattore, Alessia De Matteis, Giulia Rotunno, Giovanni A Marrocco, Stefano Nobile, Lucia Giordano, Milena Tana and Giovanni Vento
Funding Agency and Grant Number
Corresponding Author	Stefano Nobile, Adjunct Professor, MD, PhD, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy, Largo Francesco Vito 1, Rome 00168, Italy. stefano.nobile@policlinicogemelli.it
Key Words	Chylothorax; Newborn; Lung ultrasound; Infant; Pleural effusion
Core Tip	Chylothorax is a rare but severe condition in neonates. Lung ultrasound can be useful in managing this condition, but ultrasound parameters have not been standardized thus far. In this study we propose a "measurement protocol" for chylothorax in neonates and test its usefulness for clinical practice. We retrospectively reviewed 10 cases of congenital chylothorax and measured the lung-chest wall distance, the lung-diaphragm distance and the derived area. Receiver operating characteristic curves showed strong predictive value for the proposed measurements determining the need for chest tube drainage. Chest ultrasound may be a valuable tool in the management of neonates with chylothorax.
Citation	Perri A, Sbordone A, Fattore S, De Matteis A, Rotunno G, Marrocco GA, Nobile S, Lucia Giordano, Tana M, Vento G. Neonatal chylothorax and ultrasound: Diagnosis, measurements, and correlations with management. World J Clin Pediatr 2026; In press

Received	2025-12-18 01:30
Peer-Review Started	2025-12-18 01:31
First Decision by Editorial Office Director	2026-01-20 09:15
Return for Revision	2026-01-20 09:15
Revised	2026-01-30 15:32
Publication Fee Transferred
Second Decision by Editor	2026-03-24 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-24 03:48
Articles in Press	2026-03-24 03:48
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com