Publication Name	World Journal of Diabetes
Manuscript ID	117952
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Editorial
Article Title	Toward precision metabolic medicine: Multi-omics deconstruction and translational potential of herbal formulations in glycolipid metabolic disorders
Manuscript Source	Invited Manuscript
All Author List	Huo-Xiang Zhou, Wei Guo, Wei-Wei Lin, Fang Xu and Li-Yun Zheng
Funding Agency and Grant Number	Funding Agency Grant Number Key Scientific and Technological Project of Henan Province No.252102310044 Natural Science Foundation of Henan No.252300423870 Basic Research Foundation of Henan Institute of Medical and Pharmacological Sciences No.2024BP0301 and No.2025BP0201.
Corresponding Author	Li-Yun Zheng, PhD, Professor, Henan Key Laboratory of Health Medicine and Liver Disease Prevention & Treatment, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, No. 40 North Daxue Road, Zhengzhou 450052, Henan Province, China. zhengliyun@zzu.edu.cn
Key Words	Glycolipid metabolism; Traditional Chinese medicine; Herbal formulations; Multi-omics; Precision medicine
Core Tip	Multi-omics technologies are transforming the research paradigm of traditional Chinese medicine (TCM), transitioning it from an experience-based practice to an evidence-based science. The integrated transcriptomic and metabolomic study of the Jiangtang Tiaozhi Formula exemplifies how such approaches can systematically elucidate the “multi-component, multi-target” mechanisms of herbal formulations by revealing the regulation of gene networks and metabolic pathways in complex diseases, such as glycolipid metabolic disorder. Thus, the synergistic integration of traditional knowledge with modern systems biology provides a clear direction for the development of precise, mechanism-driven TCM therapies, promoting their incorporation into contemporary precision medicine.
Citation	Zhou HX, Guo W, Lin WW, Xu F, Zheng LY. Toward precision metabolic medicine: Multi-omics deconstruction and translational potential of herbal formulations in glycolipid metabolic disorders. World J Diabetes 2026; In press

Received	2025-12-22 06:45
Peer-Review Started	2025-12-23 00:20
First Decision by Editorial Office Director	2026-01-14 05:51
Return for Revision	2026-01-14 05:51
Revised	2026-01-28 01:58
Publication Fee Transferred
Second Decision by Editor	2026-02-25 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-25 06:31
Articles in Press	2026-02-25 06:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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