Publication Name	World Journal of Nephrology
Manuscript ID	118160
Country	India

Category	Medicine, General & Internal
Manuscript Type	Retrospective Cohort Study
Article Title	Multicentre comparative study of neural epidermal growth factor-like 1 protein vs M-type phospholipase A2 receptor-associated membranous nephropathy
Manuscript Source	Invited Manuscript
All Author List	Subrahmanian Sathiavageesan, Abirami Krishnan, Krishnaswamy Sampathkumar and Ranjanee Muthu
Funding Agency and Grant Number
Corresponding Author	Subrahmanian Sathiavageesan, Chief Physician, MD, Department of Nephrology, Sundaram Hospital, 17, EVR Road, Puthur, Tiruchirappalli 620017, Tamil Nādu, India. spssubrahmanian@yahoo.co.in
Key Words	Glomerulonephritis; Membranous nephroparhy; Nephrotic syndrome; Neural epidermal growth factor-like 1; M-type phospolipase A2 receptor
Core Tip	This retrospective cohort study is the first study that directly compared the outcomes of neural epidermal growth factor-like 1 protein-associated MN (NELL1-MN) with M-type phospholipase A2 receptor-associated MN (PLA2R-MN) using time-to-event analysis. NELL1-MN showed a favourable prognosis with a higher rate of remission, faster time-to-remission, more spontaneous remission and a lower rate of treatment-resistant nephrotic syndrome compared to PLA2R-MN. Additionally, this study also observed that NELL1-MN was more strongly associated with traditional indigenous medicine intake than PLA2R-MN. Antigen-specific outcomes research could inform prognosis and aid therapeutic decision-making.
Citation	Sathiavageesan S, Krishnan A, Sampathkumar K, Muthu R. Multicentre comparative study of neural epidermal growth factor-like 1 protein vs M-type phospholipase A2 receptor-associated membranous nephropathy. World J Nephrol 2026; In press

Received	2025-12-25 01:15
Peer-Review Started	2025-12-25 01:15
First Decision by Editorial Office Director	2026-01-09 08:58
Return for Revision	2026-01-09 08:58
Revised	2026-01-11 19:43
Publication Fee Transferred
Second Decision by Editor	2026-02-12 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-12 09:47
Articles in Press	2026-02-12 09:47
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6124 (online)
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