Publication Name	World Journal of Diabetes
Manuscript ID	118206
Country	China

Category	Cell Biology
Manuscript Type	Letter to the Editor
Article Title	Hepatic multi-omics insights into Jiangtang tiaozhi formula for glycolipid metabolic disorders
Manuscript Source	Invited Manuscript
All Author List	Jia-Yu Lin, Jia-Jie Fu and Di-Guang Wen
Funding Agency and Grant Number
Corresponding Author	Di-Guang Wen, School of Medical Imaging, Hangzhou Medical College, No 8 Yikang Street, Lin’an District, Hangzhou 310059, Zhejiang Province, China. 2018110626@stu.cqmu.edu.cn
Key Words	Diabetic nephropathy; Combination therapy; Sodium-glucose cotransporter 2 inhibitors; Glucagon-like peptide-1 receptor agonists; Precision medicine; Patient stratification
Core Tip	Diabetic kidney disease (DKD) is a biologically heterogeneous condition, and uniform treatment strategies may not yield equivalent benefits across patients. Recent real-world evidence supports the use of combined sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists as part of a layered therapeutic approach. This commentary highlights the importance of precision patient selection, stage-specific evaluation, and mechanism-informed decision-making to optimize combination therapy. Integrating clinical phenotypes with emerging biological insights may facilitate more individualized and effective management of DKD.
Citation	Lin JY, Fu JJ, Wen DG. Hepatic multi-omics insights into Jiangtang tiaozhi formula for glycolipid metabolic disorders. World J Diabetes 2026; In press

Received	2025-12-28 04:48
Peer-Review Started	2025-12-30 07:26
First Decision by Editorial Office Director	2026-01-06 06:35
Return for Revision	2026-01-06 06:35
Revised	2026-01-12 05:45
Publication Fee Transferred
Second Decision by Editor	2026-01-21 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-21 06:34
Articles in Press	2026-01-21 06:34
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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