Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	118321
Country	Oman

Category	Ophthalmology
Manuscript Type	Observational Study
Article Title	Systemic outcomes of anesthesia method in anti-vascular endothelial growth factor therapy for retinopathy of prematurity: General vs topical
Manuscript Source	Invited Manuscript
All Author List	Asaad A Al Habsi, Hilal K Al Mandhari, Anuradha S Ganesh, Sana S Al zuhaibi, Nasra S Al Habsi and Nouf H Al-Farsi
Funding Agency and Grant Number
Corresponding Author	Nouf H Al-Farsi, Chief Physician, FRCS, MD, Department of Ophthalmology, Sultan Qaboos University Hospital, University Medical City, P.O. Box 38 P.C. 123 Al-Khoud, Muscat 123, Oman. noufalfarsi@gmail.com
Key Words	Retinopathy of prematurity; General anesthesia; Topical anesthesia; Anti- vascular endothelial growth factor injection
Core Tip	To date, no studies have compared the short-term systemic effects of general anesthesia (GA) in infants undergoing Anti- vascular endothelial growth factor injections vs those treated at bedside with topical anesthesia. This study addressed this gap by retrospectively analyzing outcomes under GA and comparing them to prospective data from bedside procedures under topical anesthesia. Topical anesthesia as compared to GA is associated with a significantly reduced need for oxygen/and or respiratory support within 48 hours post-procedure. In addition, topical anesthesia showed better performance in duration, cost, and surgeon preference.
Citation	Al Habsi AA, Al Mandhari HK, Ganesh AS, Al Zuhaibi SS, Al Habsi NS, Al-Farsi NH. Systemic outcomes of anesthesia method in anti-vascular endothelial growth factor therapy for retinopathy of prematurity: General vs topical. World J Clin Pediatr 2026; In press

Received	2025-12-29 03:35
Peer-Review Started	2025-12-29 03:35
First Decision by Editorial Office Director	2026-01-26 08:51
Return for Revision	2026-01-26 08:51
Revised	2026-02-06 16:17
Publication Fee Transferred
Second Decision by Editor	2026-03-24 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-24 07:28
Articles in Press	2026-03-24 07:28
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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