Publication Name	World Journal of Gastroenterology
Manuscript ID	118323
Country	South Korea

Category	Oncology
Manuscript Type	Observational Study
Article Title	Serial circulating tumor DNA as a biomarker for monitoring and prognostication in patients with pancreatic cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Kwangrok Jung, Jongchan Lee, Dayeon Jang, Jinwoo Ahn, Bomi Kim, Soomin Yang, Jae Hyeong Kim, Yuna Youn, Jong-Chan Lee, Jaihwan Kim and Jin-Hyeok Hwang
Funding Agency and Grant Number	Funding Agency Grant Number National Research Foundation of Korea RS-2021-NR059201 Seoul National University Bundang Hospital Research Fund 06-2019-0069
Corresponding Author	Jin-Hyeok Hwang, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si 13620, Gyeonggi-do, South Korea. woltoong@snu.ac.kr
Key Words	Circulating tumor DNA; Pancreatic ductal adenocarcinoma; Liquid biopsy; Serial monitoring; Treatment response; Prognosis
Core Tip	This study highlights the emerging role of circulating tumor DNA (ctDNA) as a clinically relevant biomarker in pancreatic ductal adenocarcinoma. ctDNA offers a minimally invasive approach for serial disease monitoring and may provide complementary information to conventional imaging and tumor markers for treatment assessment and prognostication. In the setting of limited effective biomarkers for this malignancy, ctDNA represents a promising tool for improving clinical management.
Citation	Jung K, Lee J, Jang D, Ahn J, Kim B, Yang S, Kim JH, Youn Y, Lee JC, Kim J, Hwang JH. Serial circulating tumor DNA as a biomarker for monitoring and prognostication in patients with pancreatic cancer. World J Gastroenterol 2026; In press

Received	2025-12-30 06:46
Peer-Review Started	2025-12-30 06:51
First Decision by Editorial Office Director	2026-01-08 09:55
Return for Revision	2026-01-08 09:55
Revised	2026-01-30 15:55
Publication Fee Transferred	2026-02-09 06:54
Second Decision by Editor	2026-03-18 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-18 05:50
Articles in Press	2026-03-18 05:50
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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