Publication Name	World Journal of Clinical Cases
Manuscript ID	118410
Country	China

Category	Neuroimaging
Manuscript Type	Minireviews
Article Title	Herbal medicine for mild cognitive impairment: Neuroimaging perspectives
Manuscript Source	Unsolicited Manuscript
All Author List	Yu-Qi Zhang
Funding Agency and Grant Number
Corresponding Author	Yu-Qi Zhang, Researcher, Department of Geriatrics, Harbin Traditional Chinese Medicine Hospital, No. 270A, Jianguo Street, Daoli District, Harbin 150010, Heilongjiang Province, China. zhangyu-qi@outlook.com
Key Words	Mild cognitive impairment; Dementia; Herbal medicine; Neuroimaging biomarker; Perspective
Core Tip	Mild cognitive impairment (MCI) is a critical and potentially reversible stage preceding dementia, yet current pharmacological options offer limited benefit. This review highlights herbal medicines as multi-target interventions acting on neuroinflammation, cholinergic dysfunction, cerebral metabolism, and the gut-brain axis. Importantly, converging evidence from multimodal neuroimaging, including structural magnetic resonance imaging, functional magnetic resonance imaging, positron emission tomography, and diffusion tensor imaging, demonstrates measurable brain structural, functional, and metabolic benefits of standardized herbal interventions. Integrating neuroimaging biomarkers with phytochemical standardization and artificial intelligence may accelerate precision, disease-modifying strategies for MCI.
Citation	Zhang YQ. Herbal medicine for mild cognitive impairment: Neuroimaging perspectives. World J Clin Cases 2026; In press

Received	2026-01-04 08:27
Peer-Review Started	2026-01-04 08:28
First Decision by Editorial Office Director	2026-01-09 07:48
Return for Revision	2026-01-09 07:48
Revised	2026-01-30 12:54
Publication Fee Transferred
Second Decision by Editor	2026-04-20 02:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-20 09:21
Articles in Press	2026-04-20 09:21
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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