Publication Name	World Journal of Biological Chemistry
Manuscript ID	118440
Country	Cameroon

Category	Endocrinology & Metabolism
Manuscript Type	Case Control Study
Article Title	Glycemic status, antioxidant enzyme and lipid peroxidation among patients with diabetes mellitus in Buea Regional Hospital in Cameroon
Manuscript Source	Unsolicited Manuscript
All Author List	Ebot Walter Ojong, Leon Brandon Nyake Mbu Akime, Ayuk Betrand Tambe, Armel Jackson Seukep, Elvis Amih Ofon, Tabe Cletus Akwa and Chugbe Nathaneal Sawah
Funding Agency and Grant Number
Corresponding Author	Ebot Walter Ojong, Academic Fellow, Lecturer, PhD, Medical Laboratory Science, Faculty of Health Sciences, University of Buea, Molyko Quarter, Buea P.O. Box 63, South-West, Cameroon. ebot.ojong@ubuea.cm
Key Words	Type 2 diabetes mellitus; Glycemic control; Lipid peroxidation; Oxidative stress; Antioxidant; Buea
Core Tip	Hyperglycemia in type 2 diabetes mellitus (T2DM) generates free radicals which reduce antioxidant enzyme activities leading to oxidative stress. The influence of glycemic control on enhanced free-radical activity is poorly understood and no study has been conducted in Buea Health District. This hospital-based case-control study evaluated levels of malondialdehyde and catalase in patients with T2DM with different glycemic status and compared them with healthy subjects. We found a higher prevalence of lipid peroxidation and a higher proportion of reduced serum antioxidant activity in patients with T2DM with poor glycemic control. Routine assessment of lipid peroxidation markers and antioxidant enzyme activities in patients with T2DM especially those with poor glycemic control is recommended in improving patient care and mitigating complications.
Citation	Ojong EW, Nyake Mbu Akime LB, Tambe AB, Seukep AJ, Ofon EA, Akwa TC, Sawah CN. Glycemic status, antioxidant enzyme and lipid peroxidation among patients with diabetes mellitus in Buea Regional Hospital in Cameroon. World J Biol Chem 2026; In press

Received	2026-01-04 08:48
Peer-Review Started	2026-01-04 08:49
First Decision by Editorial Office Director	2026-01-20 08:22
Return for Revision	2026-01-20 08:22
Revised	2026-02-03 08:20
Publication Fee Transferred	2026-03-08 16:50
Second Decision by Editor	2026-05-21 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-21 10:08
Articles in Press	2026-05-21 10:08
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8454 (online)
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