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Publication Name World Journal of Gastroenterology
Manuscript ID 118510
Country China
Category Gastroenterology & Hepatology
Manuscript Type Clinical Trials Study
Article Title Cold water infusion enhances image quality in sedated miniprobe endoscopic ultrasonography: A prospective, multicenter, double-blind, randomized trial
Manuscript Source Unsolicited Manuscript
All Author List Xia-Yu Mao, Ming-Mei Ye, Xiao-Yu Yu, Jiang-Tao Liao, Yang Hu, Min Guo, Bin Zeng, Juan Li, Liu Peng, Wen-Fang Hu, Han Liu, Pan Gong, Yu Long, Xiao-Yan Wang and Li Tian
Funding Agency and Grant Number
Corresponding Author Li Tian, MD, PhD, Department of Gastroenterology, The Third Xiangya Hospital of Central South University, No. 138 Tongzipo Road, Yuelu District, Changsha 410013, Hunan Province, China. tianlixy3@csu.edu.cn
Key Words Miniprobe endoscopic ultrasonography; Infusion water temperature; Sedation; Image quality; Diagnostic accuracy
Core Tip Cold water (6-10 °C) significantly improves image quality and suppresses gastrointestinal peristalsis during sedated miniprobe endoscopic ultrasonography. Our multicenter trial showed higher rates of high-quality images (88.8% vs 75.0% vs 65.0%) and numerically higher diagnostic accuracy with cold water compared with warm (20-24 °C) and hot (35-39 °C) water. With excellent safety and comparable comfort, cold water may be the optimal temperature choice for miniprobe endoscopic ultrasonography under sedation.
Citation Mao XY, Ye MM, Yu XY, Liao JT, Hu Y, Guo M, Zeng B, Li J, Peng L, Hu WF, Liu H, Gong P, Long Y, Wang XY, Tian L. Cold water infusion enhances image quality in sedated miniprobe endoscopic ultrasonography: A prospective, multicenter, double-blind, randomized trial. World J Gastroenterol 2026; In press
Received
2026-01-05 07:23
Peer-Review Started
2026-01-05 07:24
First Decision by Editorial Office Director
2026-02-25 08:40
Return for Revision
2026-02-25 08:40
Revised
2026-03-10 13:21
Publication Fee Transferred
2026-03-11 17:34
Second Decision by Editor
2026-04-10 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-10 07:29
Articles in Press
2026-04-10 07:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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