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Publication Name World Journal of Gastroenterology
Manuscript ID 118570
Country Australia
Category Oncology
Manuscript Type Prospective Study
Article Title Stereotactic body radiotherapy for hepatocellular carcinoma: Five-year prospective registry outcomes from an Australian tertiary transplant centre
Manuscript Source Unsolicited Manuscript
All Author List Su Chen Fong, Sweet Ping Ng, Dominic Italiano, William Chung, Karl Vaz, Michael Fink, Mark Goodwin, Dinesh Ranatunga and Richard Khor
Funding Agency and Grant Number
Corresponding Author Su Chen Fong, Consultant, Research Fellow, Department of Radiation Oncology, Olivia Newton-John Cancer Centre at Austin Health, No. 145 Studley Road, Melbourne 3084, Victoria, Australia. fongsc.ro3@gmail.com
Key Words Hepatocellular carcinoma; Stereotactic body radiotherapy; Liver-directed therapy; Local control; Treatment toxicity; Prospective registry; Bridging therapy; Salvage treatment
Core Tip The role of stereotactic body radiotherapy (SBRT) in hepatocellular carcinoma is evolving within contemporary treatment guidelines. In this prospective real-world registry, SBRT achieved durable local control with minimal toxicity across curative, bridging-to-transplant, and salvage indications, including patients with impaired liver function and advanced disease. Despite excellent in-field control, out-of-field intrahepatic progression was the dominant failure pattern, highlighting the importance of integrating SBRT within multidisciplinary, stage-adapted treatment pathways.
Citation Fong SC, Ng SP, Italiano D, Chung W, Vaz K, Fink M, Goodwin M, Ranatunga D, Khor R. Stereotactic body radiotherapy for hepatocellular carcinoma: Five-year prospective registry outcomes from an Australian tertiary transplant centre. World J Gastroenterol 2026; In press
Received
2026-01-07 05:52
Peer-Review Started
2026-01-07 05:52
First Decision by Editorial Office Director
2026-02-26 07:34
Return for Revision
2026-02-26 07:34
Revised
2026-03-12 07:14
Publication Fee Transferred
2026-03-20 01:52
Second Decision by Editor
2026-04-27 02:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-27 06:32
Articles in Press
2026-04-27 06:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com