Publication Name	World Journal of Orthopedics
Manuscript ID	118601
Country	United States

Category	Orthopedics
Manuscript Type	Case Control Study
Article Title	Impact of fracture patterns and patient factors on distal interlocking screw backout after retrograde femoral nailing
Manuscript Source	Unsolicited Manuscript
All Author List	Elizabeth H G Turner, Kashif Javid, Kate L Fitzgerald, Benjamin Brennan, William M Hakeos, Lindsay M Maier, Joseph Hoegler and Stuart T Guthrie
Funding Agency and Grant Number
Corresponding Author	Kashif Javid, Department of Orthopaedic Surgery, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI 48202, United States. kjavid1@hfhs.org
Key Words	Trauma; Intramedullary nailing; Distal interlocking screw backout; Femoral fracture; Retrograde nailing
Core Tip	The purpose of our study was to evaluate patient and fracture-related factors associated with distal interlocking screw backout after retrograde femoral nailing with the DePuy Synthes Retrograde Femoral Nail-Advanced Retrograde Femoral Nailing System. Older age was significantly associated with higher rates of screw backout, with affected patients averaging 68 years compared to 38 years in the non-backout group. Fracture lines located closer to the joint line on both anterior-posterior and lateral radiographs were associated with increased risk of screw backout. No significant associations were found between screw backout and comorbidities such as smoking, diabetes, or body mass index. These findings suggest that certain fracture patterns and older patients may require careful consideration when using the DePuy Synthes Retrograde Femoral Nail-Advanced Retrograde Femoral Nailing System device.
Citation	Turner EHG, Javid K, Fitzgerald KL, Brennan B, Hakeos WM, Maier LM, Hoegler J, Guthrie ST. Impact of fracture patterns and patient factors on distal interlocking screw backout after retrograde femoral nailing. World J Orthop 2026; In press

Received	2026-01-12 03:35
Peer-Review Started	2026-01-12 03:35
First Decision by Editorial Office Director	2026-02-09 09:29
Return for Revision	2026-02-09 09:29
Revised	2026-02-23 09:19
Publication Fee Transferred
Second Decision by Editor	2026-04-20 02:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-20 10:21
Articles in Press	2026-04-20 10:21
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-5836 (online)
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