Publication Name	World Journal of Cardiology
Manuscript ID	118635
Country	Greece

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Correspondence
Article Title	Letter to the Editor: Reassessing intravenous antihypertensive choice in coronary artery disease-related hypertensive emergencies
Manuscript Source	Invited Manuscript
All Author List	Nikolaos Ktenopoulos, Nikias Milaras, Anastasios Apostolos, Konstantinos Tsioufis, Konstantinos Toutouzas and Skevos Sideris
Funding Agency and Grant Number
Corresponding Author	Nikias Milaras, MD, First Department of Cardiology, “Hippokration“ General Hospital, National and Kapodistrian University of Athens, Vasilisis Sofias 14, Athens 11527, Greece. nikiasmilaras@gmail.com
Key Words	Hypertensive emergencies; Coronary artery disease; Nitroglycerin; Labetalol; Intravenous antihypertensive therapy; Myocardial ischemia
Core Tip	Chaudhary et al provide large real-world evidence in coronary artery disease-associated hypertensive emergency comparing intravenous nitroglycerin with labetalol. Labetalol achieved target blood pressure faster, but nitroglycerin produced greater blood pressure reduction, fewer bradycardic events, smaller biomarker rises, shorter intensive care unit/hospital stays, and fewer 30-day readmissions. These results support phenotype-driven therapy, that labetalol when heart rate control is paramount, and nitroglycerin when ischemia, pulmonary congestion or myocardial injury risk dominate. Prospective validation is required before practice-changing recommendations.
Citation	Ktenopoulos N, Milaras N, Apostolos A, Tsioufis K, Toutouzas K, Sideris S. Letter to the Editor: Reassessing intravenous antihypertensive choice in coronary artery disease-related hypertensive emergencies. World J Cardiol 2026; In press

Received	2026-01-07 03:45
Peer-Review Started	2026-01-07 03:46
First Decision by Editorial Office Director	2026-01-28 08:40
Return for Revision	2026-01-28 08:40
Revised	2026-02-07 10:13
Publication Fee Transferred
Second Decision by Editor	2026-04-13 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-13 09:50
Articles in Press	2026-04-13 09:50
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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