Publication Name	World Journal of Hepatology
Manuscript ID	118665
Country	Argentina

Category	Virology
Manuscript Type	Letter to the Editor
Article Title	Respiratory syncytial virus in cirrhosis: Time to separate data from dogma?
Manuscript Source	Invited Manuscript
All Author List	Jorge Quarleri and María Victoria Delpino
Funding Agency and Grant Number
Corresponding Author	Jorge Quarleri, PhD, Principal Investigator, Professor, Senior Researcher, Tenured Professor, Instituto de Investigaciones Biomédicas en Retrovirus y Sida, Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Paraguay 2155, Buenos Aires C1121ABG, Argentina. quarleri@fmed.uba.ar
Key Words	Respiratory syncytial virus; Cirrhosis; Vaccine; Influenza virus; SARS-CoV-2; COVID-19
Core Tip	Although cirrhosis is frequently categorized as a high-risk condition for adult respiratory syncytial virus (RSV) infection, direct evidence supporting this classification remains limited. Recent real-world data indicate that RSV-related hospitalizations among patients with cirrhosis are uncommon and not independently associated with increased mortality, in contrast to the well-established risk observed in cardiopulmonary and renal diseases. Consequently, current RSV vaccination recommendations for individuals with cirrhosis rely largely on extrapolation rather than robust cirrhosis-specific evidence. Until stronger data become available, RSV vaccination in cirrhosis should be individualized, taking into account age and co-morbidities, while prioritizing multicenter studies to better define true risk and clinical benefit.
Citation	Quarleri J, Delpino MV. Respiratory syncytial virus in cirrhosis: Time to separate data from dogma? World J Hepatol 2026; In press

Received	2026-01-08 06:41
Peer-Review Started	2026-01-08 06:41
First Decision by Editorial Office Director	2026-01-16 06:48
Return for Revision	2026-01-16 06:48
Revised	2026-01-16 18:38
Publication Fee Transferred
Second Decision by Editor	2026-02-06 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-06 12:06
Articles in Press	2026-02-06 12:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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