Publication Name	World Journal of Clinical Oncology
Manuscript ID	118670
Country	Italy

Category	Oncology
Manuscript Type	Meta-Analysis
Article Title	Impact of surgery for colorectal cancer liver metastasis: Systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Fausto Petrelli, Sara Cherri, Antonio Ghidini, Mauro Rossitto, Roberta Bukovec, Luisa Roncari, Lorenzo Dottorini, Marcella Arru, Michela Libertini and Alberto Zaniboni
Funding Agency and Grant Number
Corresponding Author	Sara Cherri, Department of Oncology, Fondazione Poliambulanza, Via Bissolati 57, Brescia 25124, Italy. sara.m.cherri@gmail.com
Key Words	Colorectal cancer; Liver metastases; Surgery; Survival; Meta-analysis
Core Tip	The survival benefit of surgical resection for colorectal liver metastases has been debated, particularly in heterogeneous clinical settings. This systematic review and meta-analysis synthesizes available evidence and shows that surgery is associated with improved overall and progression-free survival compared with non-surgical approaches, although heterogeneity is substantial and most data are observational. Future studies should focus on defining predictive factors for benefit and identifying patient subgroups in whom alternative strategies may be more appropriate.
Citation	Petrelli F, Cherri S, Ghidini A, Rossitto M, Bukovec R, Roncari L, Dottorini L, Arru M, Libertini M, Zaniboni A. Impact of surgery for colorectal cancer liver metastasis: Systematic review and meta-analysis. World J Clin Oncol 2026; In press

Received	2026-01-08 07:26
Peer-Review Started	2026-01-08 07:30
First Decision by Editorial Office Director	2026-01-19 08:00
Return for Revision	2026-01-19 08:00
Revised	2026-02-06 13:39
Publication Fee Transferred	2026-02-17 07:51
Second Decision by Editor	2026-03-18 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-18 03:05
Articles in Press	2026-03-18 03:05
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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