Publication Name	World Journal of Psychiatry
Manuscript ID	118752
Country	China

Category	Psychiatry
Manuscript Type	Opinion Review
Article Title	Multidimensional risk network and clinical management of depression after intracerebral hemorrhage
Manuscript Source	Invited Manuscript
All Author List	Lu-Yin Chen, Zhou-Can Xu, Xiao-Yong Lv, Juan Ni and Xue-Jian Wang
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Program of Nantong City Key003 and JCZ2022040 Nantong Young Medical Expert No.41 the Science and Technology Program of Nantong Health Committee MA2019003 the Science and Technology Program of Nantong Health Committee MA2021017 the Science and Technology Program of Nantong Health Committee MSZ2024038 the Science and Technology Program of Nantong Health Committee MSZ2025012 Kangda College of Nanjing Medical University KD2021JYYJYB025 Kangda College of Nanjing Medical University KD2022KYJJZD022 Kangda College of Nanjing Medical University KD2024KYJJZD289 Kangda College of Nanjing Medical University KD2025JYYJZD009 Kangda College of Nanjing Medical University KD2022KYJJZD028 Research Project on Teaching Reform of Nantong University 2025J23 Jiangsu Province Occupational Health Research Project JSZJ20251217
Corresponding Author	Xue-Jian Wang, Department of Neurosurgery, Nantong Hospital Affiliated to Southeast University, No. 702 East, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com
Key Words	Cerebral haemorrhage; Post-stroke depression; Predictive model; Risk stratification; Clinical management
Core Tip	Intracerebral hemorrhage accounts for approximately half of the incidence and mortality of stroke. The early mortality rate can be as high as 40%-50%, approximately twice that of ischemic stroke. Among them, more than one-third of the survivors develop post-stroke depression. This article will conduct an in-depth interpretation and extended exploration of the clinical translational value of this model in promoting mental health management after stroke from the potential neurobiological, inflammatory metabolic, and psychosocial mechanisms behind it. Based on the existing limitations, it is proposed that future research should focus on external validation, mechanism exploration, long-term dynamic prediction, and the development of intervention strategies. Improve the emotional health management level of survivors of acute cerebral hemorrhage.
Citation	Chen LY, Xu ZC, Lv XY, Ni J, Wang XJ. Multidimensional risk network and clinical management of depression after intracerebral hemorrhage. World J Psychiatry 2026; In press

Received	2026-01-12 02:58
Peer-Review Started	2026-01-12 02:59
First Decision by Editorial Office Director	2026-02-10 09:16
Return for Revision	2026-02-10 09:16
Revised	2026-02-17 13:01
Publication Fee Transferred
Second Decision by Editor	2026-04-15 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-15 09:53
Articles in Press	2026-04-15 09:53
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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