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Publication Name World Journal of Nephrology
Manuscript ID 118797
Country India
Category Urology & Nephrology
Manuscript Type Minireviews
Article Title Emerging therapies and diagnostic innovations for multidrug-resistant infections in kidney allograft recipients: Challenges and future directions
Manuscript Source Invited Manuscript
All Author List Aditya Shetty and Mythri Shankar
Funding Agency and Grant Number
Corresponding Author Mythri Shankar, Associate Professor, DM, MD, Department of Nephrology, Institute of Nephro-Urology, Victoria Hospital Campus, KR Market, Bengaluru 560102, Karnataka, India. mythri.nish@gmail.com
Key Words Kidney transplantation; Multidrug-resistant bacterial infections; Kidney allograft recipients; Urinary tract infection; Bloodstream infection; Antimicrobial stewardship; Novel antimicrobial agents; Molecular rapid diagnostics; Therapeutic drug monitoring
Core Tip Multidrug-resistant bacterial infections are now a leading threat to survival and long-term graft function after kidney transplantation. This mini-review synthesizes current data on multidrug-resistant epidemiology, risk factors, and outcomes in kidney transplant recipients, and highlights emerging tools such as rapid molecular diagnostics, novel β-lactam/β-lactamase inhibitor combinations, siderophore cephalosporins, and individualized perioperative antibiotic strategies. A kidney transplant-specific antimicrobial stewardship framework is proposed to balance timely, effective therapy with preservation of allograft function and containment of resistance.
Citation Shetty A, Shankar M. Emerging therapies and diagnostic innovations for multidrug-resistant infections in kidney allograft recipients: Challenges and future directions. World J Nephrol 2026; In press
Received
2026-01-12 01:53
Peer-Review Started
2026-01-12 08:08
First Decision by Editorial Office Director
2026-02-03 09:51
Return for Revision
2026-02-03 09:51
Revised
2026-02-16 16:13
Publication Fee Transferred
Second Decision by Editor
2026-03-27 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-27 05:30
Articles in Press
2026-03-27 05:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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