Publication Name	World Journal of Critical Care Medicine
Manuscript ID	118811
Country	India

Category	Critical Care Medicine
Manuscript Type	Minireviews
Article Title	Navigating the veins: A comprehensive review of vasoactive agent infusion via peripheral routes
Manuscript Source	Invited Manuscript
All Author List	Omender Singh and Deven Juneja
Funding Agency and Grant Number
Corresponding Author	Deven Juneja, Director, MD, Institute of Critical Care Medicine, Max Super Speciality Hospital, Saket, 1 Press Enclave Road, New Delhi 110017, India. devenjuneja@gmail.com
Key Words	Central venous catheters; Intensive care unit; Intensive care; Peripheral venous lines; Vasoactive agents
Core Tip	Central venous catheters (CVCs) are traditionally used to transfuse vasopressors. However, their insertion is costly, time-consuming, requires expertise and may be associated with serious complications like bleeding and pneumothorax. Emerging evidence suggests that peripheral venous catheters (PVCs) can be safely and effectively used to administer vasopressors. Even though this may help with the rapid initiation of vasopressors and sometimes avoid the need for CVC insertion, the use of PVCs may also lead to minor complications from extravasation of vasopressors. By adopting a safety protocol that includes measures such as careful selection of insertion site and PVC size, limiting the dose and duration of vasopressors, and vigilant monitoring of the infusion site, complications may be further reduced. Safe use of vasopressors via PVCs may have far-reaching clinical implications for managing early septic shock, especially in resource-limited settings.
Citation	Singh O, Juneja D. Navigating the veins: A comprehensive review of vasoactive agent infusion via peripheral routes. World J Crit Care Med 2026; In press

Received	2026-01-12 01:47
Peer-Review Started	2026-01-12 01:47
First Decision by Editorial Office Director	2026-01-16 06:50
Return for Revision	2026-01-16 06:50
Revised	2026-01-17 18:55
Publication Fee Transferred
Second Decision by Editor	2026-02-09 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-09 06:28
Articles in Press	2026-02-09 06:28
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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