Publication Name	World Journal of Gastroenterology
Manuscript ID	118873
Country	Brazil

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Diagnostic performance of fine-needle aspiration vs fine-needle biopsy in solid pancreatic lesions based on pathologist expertise: A prospective multicenter trial
Manuscript Source	Invited Manuscript
All Author List	Antonio Afonso Miranda Neto, Vitor Ottoboni Brunaldi, Alberto Machado da Ponte Neto, Rafael Kemp, José Sebastião dos Santos, Joel Del Bel Pádua, Mariangela Ottoboni Brunaldi, Francisco Antonio Araújo Oliveira, José Ruver Lima Herculano Júnior, Danielle Azevedo Chacon, Guilherme Henrique Peixoto de Oliveira, Igor Braga Ribeiro, Sergio Eiji Matuguma and Eduardo Guimarães Hourneaux de Moura
Funding Agency and Grant Number
Corresponding Author	Igor Braga Ribeiro, Associate Research Scientist, MD, PhD, Department of Gastroenterology, University of São Paulo School of Medicine, Av. Dr Enéas de Carvalho Aguiar, 225, 6o andar, bloco 3, Cerqueira Cesar, São Paulo 05403-010, Brazil. igorbraga1@gmail.com
Key Words	Pancreatic cancer; Endoscopic ultrasound; Fine-needle aspiration; Fine-needle biopsy
Core Tip	The diagnostic yield of endoscopic ultrasound-guided tissue acquisition for solid pancreatic lesions is influenced by needle design, pathologist expertise, and institutional volume. This study shows that fine-needle biopsy provides superior diagnostic sensitivity compared with fine-needle aspiration when specimens are assessed by general pathologists, particularly in low-volume centers. These findings support fine-needle biopsy as a practical strategy to improve diagnostic reliability and reduce dependence on specialized cytopathology in routine clinical practice.
Citation	Miranda Neto AA, Brunaldi VO, da Ponte Neto AM, Kemp R, dos Santos JS, Pádua JDB, Brunaldi MO, Oliveira FAA, Herculano Júnior JRL, Chacon DA, de Oliveira GHP, Ribeiro IB, Matuguma SE, de Moura EGH. Diagnostic performance of fine-needle aspiration vs fine-needle biopsy in solid pancreatic lesions based on pathologist expertise: A prospective multicenter trial. World J Gastroenterol 2026; In press

Received	2026-01-13 06:13
Peer-Review Started	2026-01-13 06:15
First Decision by Editorial Office Director	2026-02-06 10:45
Return for Revision	2026-02-06 10:45
Revised	2026-02-13 19:37
Publication Fee Transferred
Second Decision by Editor	2026-04-13 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-13 08:55
Articles in Press	2026-04-13 08:55
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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