Publication Name	World Journal of Cardiology
Manuscript ID	118879
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Meta-Analysis
Article Title	Clinical outcomes of finerenone in heart failure: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Maneeth Mylavarapu, Madiha Kiyani, Andrew Ndakotsu, Vaibhav Vats, Nithin Karnan, Elizabeth Caroline Palaparthi, Mahnoor Anjum, Lakshmi Sai Meghana Kodali, Aneeza Jamshed and Fabio Enrique Parada Cabrera
Funding Agency and Grant Number
Corresponding Author	Maneeth Mylavarapu, MD, Senior Researcher, Department of Cardiology, Endeavor Health Cardiovascular Institute, 2100 Pfingsten Rd, Glenview, IL 60026, United States, Glenview, IL 60026, United States. dr.maneeth.mylavarapu@gmail.com
Key Words	Finerenone; Heart failure; Nonsteroidal mineralocorticoid receptor antagonists; Kansas City Cardiomyopathy Questionnaire; Hyperkalemia; Meta-analysis
Core Tip	Finerenone, a novel nonsteroidal mineralocorticoid receptor antagonist, has shown clear benefits in chronic kidney disease, but its specific impact on heart failure (HF) has required further synthesis. Our meta-analysis of 7457 patients reveals that finerenone significantly decreases the odds of worsening HF and enhances quality of life scores. However, potential safety signals, including hyperkalemia, suggest that while finerenone is a potent tool for managing HF, its use requires vigilant monitoring to balance clinical benefits against adverse events.
Citation	Mylavarapu M, Kiyani M, Ndakotsu A, Vats V, Karnan N, Palaparthi EC, Anjum M, Kodali LSM, Jamshed A, Cabrera FEP. Clinical outcomes of finerenone in heart failure: A systematic review and meta-analysis. World J Cardiol 2026; In press

Received	2026-01-13 06:15
Peer-Review Started	2026-01-13 06:16
First Decision by Editorial Office Director	2026-01-20 08:25
Return for Revision	2026-01-20 08:25
Revised	2026-02-14 01:14
Publication Fee Transferred
Second Decision by Editor	2026-03-19 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-19 06:09
Articles in Press	2026-03-19 06:09
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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