Publication Name	World Journal of Hepatology
Manuscript ID	118905
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Association between preoperative serum zinc levels and postoperative infectious complications after minimally invasive hepatectomy: A retrospective cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Hiromichi Murase, Yoichi Matsuo, Eiji Nakatani, Yuki Denda, Keisuke Nonoyama, Tomokatsu Kato, Kenta Saito, Takafumi Sato, Mamoru Morimoto, Yushi Yamakawa, Hiroyuki Sagawa and Shuji Takiguchi
Funding Agency and Grant Number
Corresponding Author	Yoichi Matsuo, Gastroenterological Surgery, Nagoya City University East Medical Center, 1-2-23 Wakamizu,Chikusa-ku,Nagoya, Nagoya 464-8547, Japan. nukemat0328@gmail.com
Key Words	Liver surgery; Minimally invasive hepatectomy; Zinc deficiency; Surgical site infection; Postoperative infection
Core Tip	In 182 minimally invasive hepatectomies (MIH), lower preoperative Zinc (Zn) concentration was associated with a higher incidence of postoperative infectious complications. Zn ≥ 80 μg/dL independently protected against infection (adjusted odds ratio = 0.318); infection rates declined stepwise with increasing Zn categories. Because Zn is measurable and modifiable preoperatively, assessment and correction may represent a simple strategy to reduce infections after MIH. Prospective studies are required.
Citation	Murase H, Matsuo Y, Nakatani E, Denda Y, Nonoyama K, Kato T, Saito K, Sato T, Morimoto M, Yamakawa Y, Sagawa H, Takiguchi S. Association between preoperative serum zinc levels and postoperative infectious complications after minimally invasive hepatectomy: A retrospective cohort study. World J Hepatol 2026; In press

Received	2026-01-14 01:14
Peer-Review Started	2026-01-14 01:15
First Decision by Editorial Office Director	2026-01-30 09:12
Return for Revision	2026-01-31 04:52
Revised	2026-02-13 09:05
Publication Fee Transferred
Second Decision by Editor	2026-04-23 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-23 10:36
Articles in Press	2026-04-23 10:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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