Publication Name	World Journal of Gastroenterology
Manuscript ID	119106
Country	Moldova

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Preventive strategies in hepatology: Role of multiparametric assessment of portal hypertension in chronic liver disease
Manuscript Source	Invited Manuscript
All Author List	Angela Peltec and Ioan Sporea
Funding Agency and Grant Number
Corresponding Author	Angela Peltec, Associate Professor, MD, PhD, Discipline of Gastroenterology, Department of Internal Medicine, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Str. Testemitanu 29, Chishinev 2019, Moldova. angela.peltec@usmf.md
Key Words	Preventive hepatology; Advanced chronic liver disease; Clinically significant portal hypertension; Multiparametric ultrasound; Liver stiffness measurement; Spleen stiffness measurement
Core Tip	The goal of preventive hepatology is to reduce the burden of liver disease through early detection, risk stratification, and timely intervention. Assessing portal hypertension in patients with advanced chronic liver disease is essential for predicting decompensation and guiding clinical management. Noninvasive imaging techniques, particularly multiparametric ultrasound (MPUS), are valuable approaches for evaluating portal hemodynamics. Combining Doppler ultrasound, contrast-enhanced ultrasound, elastography, and endoscopic ultrasound, MPUS enables accurate, accessible, and radiation-free assessment of liver disease severity. The integration of MPUS into routine care will support effective screening and monitoring to ultimately improve outcomes.
Citation	Peltec A, Sporea I. Preventive strategies in hepatology: Role of multiparametric assessment of portal hypertension in chronic liver disease. World J Gastroenterol 2026; In press

Received	2026-01-19 02:56
Peer-Review Started	2026-01-19 02:57
First Decision by Editorial Office Director	2026-01-30 09:12
Return for Revision	2026-01-30 09:12
Revised	2026-02-09 22:27
Publication Fee Transferred
Second Decision by Editor	2026-04-08 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-08 10:58
Articles in Press	2026-04-08 10:58
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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