Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	119170
Country	China

Category	Ophthalmology
Manuscript Type	Retrospective Study
Article Title	Impact of anxiety and depression on quality of life in gastric cancer patients receiving SOX neoadjuvant chemotherapy
Manuscript Source	Unsolicited Manuscript
All Author List	Bo-Yang Cui and Zhen Zhang
Funding Agency and Grant Number
Corresponding Author	Zhen Zhang, Lecturer, Department of Thoracic Surgery, The Second Affiliated Hospital of Kunming Medical University, No. 374 Dianmian Avenue, Wuhua District, Kunming 650000, Yunnan Province, China. 15987129313@163.com
Key Words	Anxiety; Depression; Gastric cancer; Neoadjuvant chemotherapy; Quality of life
Core Tip	This study reveals that nearly half of the patients with early-to-mid-stage gastric cancer undergoing neoadjuvant chemotherapy experience anxiety or depression. These conditions are more common in females, those without spousal support, the less educated, and those with advanced-stage disease. Critically, psychological distress is independently linked to more severe gastrointestinal reactions and a significantly poorer quality of life. Our findings underscore the urgent need for integrating routine psychological screening and support into the standard management protocol for these patients to address both mental and physical well-being.
Citation	Cui BY, Zhang Z. Impact of anxiety and depression on quality of life in gastric cancer patients receiving SOX neoadjuvant chemotherapy. World J Gastrointest Oncol 2026; In press

Received	2026-01-20 09:48
Peer-Review Started	2026-01-20 09:48
First Decision by Editorial Office Director	2026-01-28 08:00
Return for Revision	2026-01-28 08:00
Revised	2026-02-03 09:52
Publication Fee Transferred
Second Decision by Editor	2026-03-10 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-10 07:42
Articles in Press	2026-03-10 07:42
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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