Publication Name	World Journal of Experimental Medicine
Manuscript ID	119334
Country	India

Category	Ophthalmology
Manuscript Type	Correspondence
Article Title	Letter to the Editor: Eye as a window to disease burden in pediatric acute leukemia
Manuscript Source	Invited Manuscript
All Author List	Devlina Ghosh
Funding Agency and Grant Number
Corresponding Author	Devlina Ghosh, Assistant Professor, PhD, Department of Biochemistry, Saraswati Dental College & Hospital, 233 Tiwariganj, Ayodhya Road, Lucknow 226028, Uttar Pradesh, India. ghoshdevlin6@gmail.com
Key Words	Acute paediatric leukaemia; Ocular involvement; Leukemic retinopathy; Intraretinal hemorrhages; Disease burden; Ophthalmology
Core Tip	Ocular manifestations in pediatric acute leukemia are common but often underrecognized, despite reflecting underlying systemic disease burden. Retinal and optic nerve abnormalities may result from hematologic disturbances or direct leukemic infiltration and frequently occur without visual symptoms. Advances in retinal imaging have enhanced detection of overt and subclinical changes, supporting early ophthalmic assessment. This letter highlights the eye as a non-invasive indicator of disease severity and emphasizes the need for standardized screening and prospective research to improve multidisciplinary care.
Citation	Ghosh D. Letter to the Editor: Eye as a window to disease burden in pediatric acute leukemia. World J Exp Med 2026; In press

Received	2026-01-26 01:13
Peer-Review Started	2026-01-26 01:14
First Decision by Editorial Office Director	2026-02-04 09:47
Return for Revision	2026-02-04 09:47
Revised	2026-02-17 14:05
Publication Fee Transferred
Second Decision by Editor	2026-04-22 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-22 07:18
Articles in Press	2026-04-22 07:18
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-315x (online)
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