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Publication Name World Journal of Gastroenterology
Manuscript ID 119375
Country China
Category Surgery
Manuscript Type Observational Study
Article Title Clinical efficacy and safety of laparoscopic hybrid surgery for simultaneous resection of colorectal cancer liver metastases
Manuscript Source Unsolicited Manuscript
All Author List Tian-Shuai Zhang, Xiao-Ming Zhu, Rong-Bo Wen, Le-Qi Zhou, Hai-Feng Gong, En-Da Yu, Hao Wang, Gang Li, Wei-Ping Zhou, Li-Qiang Hao, Guan-Yu Yu and Wei Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82473439, 82503486
Shanghai "Rising Stars of Medical Talents" Youth Development Program of the Shanghai Municipal Health Commission, China 2024-70
Naval Medical University "Deep Blue" Project Talent Program
the First Affiliated Hospital of Naval Medical University Special Project for Basic Medical Research, China 2023QD003, 2023PY04
the First Affiliated Hospital of Naval Medical University Special Project for Clinical Research, China 2024LYA02
Shanghai Science and Technology Plan Project 25SF1901500
Corresponding Author Wei Zhang, Chief, MD, PhD, Professor, Department of Colorectal Surgery, Shanghai Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Yangpu District, Shanghai 200433, China. weizhang2000cn@163.com
Key Words Colorectal cancer; Colorectal cancer liver metastasis; Laparoscopic hybrid surgery; Simultaneous resection; Surgical approach
Core Tip The best simultaneous resection strategy for patients with colorectal cancer liver metastases remains controversial. In this study, we innovatively propose a laparoscopic hybrid surgery (LHS) approach for simultaneous resection of colorectal cancer liver metastases. Compared with totally open surgery, the incidence of complications in the LHS group was significantly lower (10.4% vs 20.5%, P = 0.022). Patients treated with LHS had a shorter postoperative length of stay, earlier postoperative intake of liquids, less blood loss, and similar survival outcomes (overall survival, P = 0.464; disease-free survival, P = 0.838) to those treated with totally open surgery.
Citation Zhang TS, Zhu XM, Wen RB, Zhou LQ, Gong HF, Yu ED, Wang H, Li G, Zhou WP, Hao LQ, Yu GY, Zhang W. Clinical efficacy and safety of laparoscopic hybrid surgery for simultaneous resection of colorectal cancer liver metastases. World J Gastroenterol 2026; In press
Received
2026-01-28 07:13
Peer-Review Started
2026-01-28 07:15
First Decision by Editorial Office Director
2026-03-17 10:22
Return for Revision
2026-03-17 10:22
Revised
2026-03-31 02:10
Publication Fee Transferred
Second Decision by Editor
2026-05-29 03:01
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-29 06:01
Articles in Press
2026-05-29 06:01
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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