Publication Name	World Journal of Hepatology
Manuscript ID	119408
Country	Saudi Arabia

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Diagnostic and prognostic utility of serum bile acid in liver transplant recipients: A systematic review and quantitative synthesis
Manuscript Source	Unsolicited Manuscript
All Author List	Eyad Gadour, Hadi Kuriry, Bogdan Miutescu, Bodour Raheem, Syed A Gardezi and Mohammed S AlQahtani
Funding Agency and Grant Number
Corresponding Author	Eyad Gadour, CCST, Consultant, FACP, FRCP, MD, MRCP, Professor, Multiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Ammar Bin Thabit Street, Dammam 32253, Saudi Arabia. eyadgadour@doctors.org.uk
Key Words	Serum bile acid; Liver transplantation; Surveillance strategies; Graft dysfunction; Graft rejection; Biliary complications
Core Tip	Serum bile acid (SBA) levels serve as a sensitive, non-invasive biomarker for early detection and prognosis of graft dysfunction, acute rejection, patient survival, and biliary complications following liver transplantation. Elevated SBA levels correlate strongly with adverse outcomes, often preceding changes in conventional liver function tests. Despite promising diagnostic accuracy, heterogeneity in assay methods and cutoff values limits routine clinical use. Standardized protocols and large multicenter prospective studies are needed to validate SBA monitoring as a complementary tool to established biochemical tests, enhancing post-transplant surveillance and timely intervention strategies.
Citation	Gadour E, Kuriry H, Miutescu B, Raheem B, Gardezi SA, AlQahtani MS. Diagnostic and prognostic utility of serum bile acid in liver transplant recipients: A systematic review and quantitative synthesis. World J Hepatol 2026; In press

Received	2026-01-27 05:59
Peer-Review Started	2026-01-27 05:59
First Decision by Editorial Office Director	2026-02-06 10:20
Return for Revision	2026-02-06 10:20
Revised	2026-02-13 11:19
Publication Fee Transferred	2026-02-17 08:56
Second Decision by Editor	2026-03-25 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-25 08:30
Articles in Press	2026-03-25 08:30
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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