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Publication Name World Journal of Transplantation
Manuscript ID 119505
DOI 10.5500/wjt.119505
Country United States
Category Transplantation
Manuscript Type Retrospective Cohort Study
Article Title Higher model for end-stage liver disease excluding international normalized ratio scores predict worse kidney graft outcomes in simultaneous heart-kidney transplantation
Manuscript Source Invited Manuscript
All Author List Marco E Diaz-Cordova, Matthew Rega, Ishani Sharma, Ryosuke Misawa, Abhay Dhand, Seigo Nishida and Kenji Okumura
Funding Agency and Grant Number
Corresponding Author Kenji Okumura, Associate Faculty, MD, Department of Surgery, Westchester Medical Center and New York Medical College, 100 Woods Road, Valhalla, NY 10595, United States. kenji.okumura@wmchealth.org
Key Words Simultaneous heart-kidney transplant; Model for end-stage liver disease excluding international normalized ratio; Heart transplant; Kidney transplant; Predictor; Transplant outcomes; Delayed graft dysfunction
Core Tip The incidence of simultaneous heart-kidney transplantation (SHKT) has increased substantially in recent years. Early studies suggested benefit, but recent data are conflicting. No reliable prognostic marker exists for this population. The model for end-stage liver disease excluding international normalized ratio (MELD-XI) was previously validated in heart transplantation and cardiac surgery and may serve as a risk-stratification tool. In this study, higher MELD-XI scores were linked to early mortality and kidney graft failure. This supports its potential role in guiding selection between SHKT and kidney-after-heart transplantation under current allocation policies.
Citation Diaz-Cordova ME, Rega M, Sharma I, Misawa R, Dhand A, Nishida S, Okumura K. Higher model for end-stage liver disease excluding international normalized ratio scores predict worse kidney graft outcomes in simultaneous heart-kidney transplantation. World J Transplant 2026; In press
PDF 119505-in-press.pdf
Received
2026-02-06 00:37
Peer-Review Started
2026-02-06 00:44
First Decision by Editorial Office Director
2026-02-25 08:06
Return for Revision
2026-02-25 08:06
Revised
2026-04-01 15:34
Publication Fee Transferred
Second Decision by Editor
2026-06-05 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-05 06:39
Articles in Press
2026-06-05 06:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com