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5/7/2026 11:49:04 AM | Browse: 4 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 119518
Country China
Category Oncology
Manuscript Type Correspondence
Article Title Letter to the editor: Role of adjuvant programmed death-1 blockade combined with chemotherapy in resected pancreatic ductal adenocarcinoma
Manuscript Source Invited Manuscript
All Author List Jin-Wei Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 82170406 and No. 81970238
Corresponding Author Jin-Wei Zhang, PhD, Principal Investigator, Professor, tate Key Laboratory of Chemical Biology, Research Center of Chemical Kinomics, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, No. 345 Lingling Road, Shanghai 200032, China. jinweizhang@sioc.ac.cn
Key Words Pancreatic ductal adenocarcinoma; Adjuvant therapy; Programmed death-1 inhibitor; Immunotherapy; Recurrence-free survival; Real-world evidence
Core Tip Although immune checkpoint inhibitors have shown minimal efficacy in advanced pancreatic cancer, the postoperative adjuvant setting may offer a biologically favorable window for immune intervention. A recent study suggested that combining programmed death-1 inhibition with chemotherapy after surgical resection may improve recurrence-related outcomes without excessive toxicity, providing a compelling rationale for prospective, biomarker-informed trials in this historically refractory disease.
Citation Zhang JW. Letter to the editor: Role of adjuvant programmed death-1 blockade combined with chemotherapy in resected pancreatic ductal adenocarcinoma. World J Gastrointest Oncol 2026; In press
Received
2026-01-30 01:02
Peer-Review Started
2026-01-30 01:02
First Decision by Editorial Office Director
2026-02-12 08:00
Return for Revision
2026-02-12 08:00
Revised
2026-02-12 12:42
Publication Fee Transferred
Second Decision by Editor
2026-05-07 03:24
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-07 11:49
Articles in Press
2026-05-07 11:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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