Publication Name	World Journal of Nephrology
Manuscript ID	119548
Country	Italy

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Renal replacement therapies in the prevention of contrast-induced acute kidney injury
Manuscript Source	Invited Manuscript
All Author List	Filippo Trombara, Nicola Cosentino, Gianluca Pontone and Giancarlo Marenzi
Funding Agency and Grant Number
Corresponding Author	Nicola Cosentino, Head, MD, PhD, Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Via Carlo Parea 4, Milan 20138, Lombardy, Italy. nicola.cosentino@cardiologicomonzino.it
Key Words	Contrast-associated acute kidney injury; Renal replacement therapy; Hemodialysis; Hemofiltration; Prevention
Core Tip	Contrast-associated acute kidney injury remains a major complication in high-risk patients undergoing contrast-based procedures. While standard prevention relies on individualized hydration and contrast minimization, the role of prophylactic renal replacement therapy remains controversial. Evidence consistently shows that hemodialysis does not prevent contrast-associated acute kidney injury, whereas early hemofiltration may offer benefit in carefully selected patients with advanced chronic kidney disease and limited tolerance to fluid expansion. However, inconsistent trial results and logistical constraints preclude routine use. This review critically evaluates current evidence, highlights patient selection and timing considerations, and underscores the need for adequately powered randomized trials.
Citation	Trombara F, Cosentino N, Pontone G, Marenzi G. Renal replacement therapies in the prevention of contrast-induced acute kidney injury. World J Nephrol 2026; In press

Received	2026-02-10 00:54
Peer-Review Started	2026-02-10 01:00
First Decision by Editorial Office Director	2026-02-13 07:34
Return for Revision	2026-02-13 07:34
Revised	2026-02-23 10:19
Publication Fee Transferred
Second Decision by Editor	2026-04-02 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-02 07:46
Articles in Press	2026-04-02 07:46
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com