Publication Name	World Journal of Gastroenterology
Manuscript ID	119574
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	High cyclin-dependent kinase 5 expression promotes tumor progression in gastric neuroendocrine carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Yu-Qin Sun, Jie Su, Kai-Ning Ye, Qiu-Xian Chen, En-Zhou Kang, Chen-Bin Lv, Ming-Qiao Lian, Wei-Ming Zeng, Yong-Bin Zhang and Li-Sheng Cai
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Fujian Province 2025J011630 Climbing Fund of PhD Workstation, Zhangzhou Affiliated Hospital of Fujian Medical University PDA202101
Corresponding Author	Li-Sheng Cai, Department of Gastrointestinal Surgery, Zhangzhou Affiliated Hospital of Fujian Medical University, No. 59 West Shengli Road, Zhangzhou 363000, Fujian Province, China. wxccls2024@163.com
Key Words	Cyclin-dependent kinase 5; Gastric neuroendocrine carcinoma; Cell proliferation; Human epidermal growth factor receptor 2; Survival
Core Tip	This study aims to investigate the expression and function of cyclin-dependent kinase 5 (CDK5) in gastric neuroendocrine carcinoma (GNEC). The findings indicate that patients with elevated CDK5 expression in GNEC have a poor prognosis. Furthermore, CDK5 is identified as an independent prognostic risk factor and may play a critical role in the proliferation of GNEC.
Citation	Sun YQ, Su J, Ye KN, Chen QX, Kang EZ, Lv CB, Lian MQ, Zeng WM, Zhang YB, Cai LS. High cyclin-dependent kinase 5 expression promotes tumor progression in gastric neuroendocrine carcinoma. World J Gastroenterol 2026; In press

Received	2026-02-02 03:26
Peer-Review Started	2026-02-02 03:26
First Decision by Editorial Office Director	2026-02-10 10:54
Return for Revision	2026-02-10 10:54
Revised	2026-02-23 02:41
Publication Fee Transferred	2026-02-25 07:15
Second Decision by Editor	2026-03-23 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-23 06:08
Articles in Press	2026-03-23 06:08
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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