Publication Name	World Journal of Gastroenterology
Manuscript ID	119608
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Association between gastroesophageal reflux disease and functional dyspepsia: A systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Ao Wang, Hong-Jie Cheng, Nai-Wei Zhang, Yan-Mei Cai, Qiao-Yan Zhang, Yi-Pan Guan, Xian-Yang Jiang, Hai-Xia Zeng and Bo-Yi Jia
Funding Agency and Grant Number	Funding Agency Grant Number Capital’s Funds for Health Improvement and Research No. CFH 2024-4-7075 National Natural Science Foundation of China No. 82004273 2026 Beijing University of Chinese Medicine Basic Scientific Research Business Fund Project for New Teacher Start-up Fund Beijing Traditional Chinese Medicine “New Era 125 Project” Talent Support Program, High-tech Plan and Peak Young Seedling Spring Bud Project
Corresponding Author	Bo-Yi Jia, PhD, Vice Director, Department of Spleen and Stomach Diseases, Fangshan Traditional Medical Hospital of Beijing, No. 4 Chengguan Jianbao Road, Fangshan District, Beijing 102400, China. jiaboyiwilliam@163.com
Key Words	Gastroesophageal reflux disease; Functional dyspepsia; Systematic review; Meta-analysis; Epidemiology
Core Tip	This meta-analysis integrates the most recent evidence to clarify the relationship between gastroesophageal reflux disease (GERD) and functional dyspepsia (FD). Pooled results indicate a strong association between GERD and FD, supporting the concept that these disorders frequently overlap in clinical practice. The findings suggest that shared pathophysiological pathways may contribute to co-occurrence, although residual confounding cannot be excluded. Improved recognition of GERD-FD overlap may help optimize evaluation strategies and guide more targeted, mechanism-based management.
Citation	Wang A, Cheng HJ, Zhang NW, Cai YM, Zhang QY, Guan YP, Jiang XY, Zeng HX, Jia BY. Association between gastroesophageal reflux disease and functional dyspepsia: A systematic review and meta-analysis. World J Gastroenterol 2026; In press

Received	2026-02-02 03:02
Peer-Review Started	2026-02-02 03:05
First Decision by Editorial Office Director	2026-02-06 10:50
Return for Revision	2026-02-06 10:50
Revised	2026-02-16 03:09
Publication Fee Transferred	2026-02-17 11:50
Second Decision by Editor	2026-04-01 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-01 06:05
Articles in Press	2026-04-01 06:05
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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