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Publication Name World Journal of Gastroenterology
Manuscript ID 119611
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Endocytoscopy for histological evaluation of inflammation in ulcerative colitis
Manuscript Source Unsolicited Manuscript
All Author List Miao Li, Xiao-Ying Lou, Zhong-Cheng Liu, Bo Peng, Yan Huang and Qin Guo
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Research & Development Program of China No. 2023YFC2507300
the Program of Guangdong Provincial Clinical Research Center for Digestive Diseases No. 2020B1111170004
National Natural Science Foundation of China No. 82302334
Guangdong Provincial Health Commission Appropriate Technology Promotion Project No. 201905242108259876
Sixth Affiliated Hospital of Sun Yat-Sen University Clinical Research “1010” Program No. 1010CG(2023)-02
Corresponding Author Qin Guo, MD, Department of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, No. 26 Yuancun Erheng Road, Tianhe District, Guangzhou 510655, Guangdong Province, China. guoq83@mail.sysu.edu.cn
Key Words Ulcerative colitis; Endocytoscopy; Endocytoscopic score; Geboes score; Histological remission; Mucosal healing
Core Tip Histological remission in ulcerative colitis (UC) can be assessed traditionally by microscopic examination of endoscopic biopsies. Recently, advanced endocytoscopy has been increasingly used for real-time evaluation of the colonic mucosa in UC. The current study developed a novel scoring system based on endocytoscopic images called as endocytoscopic score (ECSS) to evaluate endoscopic and histological remission in UC. ECSS showed strong correlation with histological changes. ECSS has high interobserver consistency and good reproducibility. ECSS can be used to stratify patients based on inflammatory activity and mucosal healing without biopsies, providing a new direction for real-time non-invasive assessment of UC.
Citation Li M, Lou XY, Liu ZC, Peng B, Huang Y, Guo Q. Endocytoscopy for histological evaluation of inflammation in ulcerative colitis. World J Gastroenterol 2026; In press
Received
2026-02-02 02:55
Peer-Review Started
2026-02-02 02:55
First Decision by Editorial Office Director
2026-02-28 08:16
Return for Revision
2026-02-28 08:16
Revised
2026-03-13 17:24
Publication Fee Transferred
2026-03-19 08:17
Second Decision by Editor
2026-05-09 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-09 11:09
Articles in Press
2026-05-09 11:09
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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