Publication Name	World Journal of Clinical Oncology
Manuscript ID	119673
Country	India

Category	Oncology
Manuscript Type	Editorial
Article Title	Prognostic significance of stem cell markers: In triple-negative breast cancers
Manuscript Source	Invited Manuscript
All Author List	Sunil V Jagtap and Shubham S Jagtap
Funding Agency and Grant Number
Corresponding Author	Sunil V Jagtap, Professor, Department of Pathology, Krishna Vishwa Vidyapeeth, Krishna Institute of Medical Sciences e mail-research@kvv.edu.in, Malkapur, Karad 415110, Maharashtra, India. drsvjagtap@gmail.com
Key Words	Triple-negative breast cancer; Cancer stem cell; Bio-markers; Prognostic Significance
Core Tip	Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by absence of estrogen, progesteron and human epidermal growth factor receptor-2 expressions. TNBC exhibit cancer stem cell (CSC)-like properties at functional, molecular, and transcriptional levels. Stemness markers described across different histological subtypes include CD44, CD24, CD133, ALDH1 and ABCG2. These markers have prognostic and predictive value in TNBC, as their expression has been associated with increased tumor aggressiveness, chemoresistance, poor prognosis, lack of effective targeted therapies and unfavorable clinical outcomes. Recent studies on CSC markers in TNBC highlight their potential as new prognostic biomarkers and targeted therapies.
Citation	Jagtap SV, Jagtap SS. Prognostic significance of stem cell markers: In triple-negative breast cancers. World J Clin Oncol 2026; In press

Received	2026-02-14 02:30
Peer-Review Started	2026-02-14 02:30
First Decision by Editorial Office Director	2026-02-25 07:58
Return for Revision	2026-02-25 07:58
Revised	2026-03-04 11:42
Publication Fee Transferred
Second Decision by Editor	2026-04-27 02:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-27 03:06
Articles in Press	2026-04-27 03:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com