Publication Name	World Journal of Diabetes
Manuscript ID	119712
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Digital health technologies for diabetes-centered five-condition co-management in China: Theoretical foundations, practical experience, and technical challenges
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Li Xu, Cheng Luo, Cheng-Zheng Duan, Shi-Yu Xu, Zhi-Qiang Wu, Li-Ya Ye, Zhi-Peng Li, Mao-Sen Wang, Xian-Mei Yu and Dong-Juan He
Funding Agency and Grant Number	Funding Agency Grant Number Quzhou Science and Technology Bureau 2025K114
Corresponding Author	Dong-Juan He, Dean, MD, Professor, Department of Endocrinology, The Second People’s Hospital of Quzhou, No. 338 Xin’an Avenue, Qujiang District, Quzhou 324000, Zhejiang Province, China. hedongjuan1247@wmu.edu.cn
Key Words	Artificial intelligence; Cardiometabolic risk; Chronic disease management; Digital health; Dyslipidemia; Hypertension; Hyperuricemia; Obesity; Precision medicine; Type 2 diabetes mellitus
Core Tip	Diabetes-centered five-condition co-management integrates glycemic control with concurrent management of hypertension, dyslipidemia, hyperuricemia, and obesity to address shared cardiometabolic pathophysiology and synergistic risk amplification. This review synthesizes the epidemiologic rationale, mechanistic links, and evidence from digital health-enabled care models, highlighting how continuous monitoring, personalized decision support, and multidisciplinary workflows can improve target attainment and adherence. We propose a practical implementation framework with measurable endpoints, risk stratification, and governance requirements for artificial intelligence tools, while outlining barriers such as interoperability, equity, and long-term safety and effectiveness evaluation in real-world settings.
Citation	Xu JL, Luo C, Duan CZ, Xu SY, Wu ZQ, Ye LY, Li ZP, Wang MS, Yu XM, He DJ. Digital health technologies for diabetes-centered five-condition co-management in China: Theoretical foundations, practical experience, and technical challenges. World J Diabetes 2026; In press

Received	2026-02-04 00:24
Peer-Review Started	2026-02-08 02:16
First Decision by Editorial Office Director	2026-03-20 10:10
Return for Revision	2026-03-20 10:10
Revised	2026-03-31 02:31
Publication Fee Transferred
Second Decision by Editor	2026-05-19 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-19 08:25
Articles in Press	2026-05-19 08:25
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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