Publication Name	World Journal of Stem Cells
Manuscript ID	119714
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Clinical significance of mesenchymal stem cells exosomal microRNAs in predicting prognosis and inflammatory response of esophageal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Jin-Lin Wang, Ya-Xuan Niu, Han-Xiao Li, Fa-Cai Cui and Xiao Chen
Funding Agency and Grant Number
Corresponding Author	Fa-Cai Cui, Chief Physician, Clinical Laboratory, Henan Provincial People’s Hospital, No. 7 Weiwu Road, Zhengzhou 450003, Henan Province, China. cuifacai1985@zzu.edu.cn
Key Words	Esophageal squamous cell carcinoma; miR-375; miR-655; Inflammatory factors; Prognosis; Mesenchymal stem cells; Exosome
Core Tip	Overexpression of miR-375 and miR-655 in peripheral blood mesenchymal stem cells exosomes derived from patients is associated with inflammatory factors and unfavorable prognosis in esophageal squamous cell carcinoma. Their combined evaluation provides improved prognostic stratification and may serve as a valuable adjunct for individualized clinical management. The findings aim to provide new evidence for the biological and clinical relevance of these biomarkers and offer a reference for personalized prognosis assessment and clinical decision-making in esophageal squamous cell carcinoma management.
Citation	Wang JL, Niu YX, Li HX, Cui FC, Chen X. Clinical significance of mesenchymal stem cells exosomal microRNAs in predicting prognosis and inflammatory response of esophageal cancer. World J Stem Cells 2026; In press

Received	2026-02-27 10:11
Peer-Review Started	2026-02-27 10:12
First Decision by Editorial Office Director	2026-03-13 09:06
Return for Revision	2026-03-13 09:06
Revised	2026-03-19 03:17
Publication Fee Transferred	2026-03-25 01:54
Second Decision by Editor	2026-05-12 03:24
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-19 08:51
Articles in Press	2026-05-19 08:51
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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