Publication Name	World Journal of Gastroenterology
Manuscript ID	119809
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Perioperative SOX plus sintilimab vs P-SOX and CAPOX in advanced gastric cancer: A real-world comparison
Manuscript Source	Unsolicited Manuscript
All Author List	Di-Xia Zhou, Shao-Wei Jiang, Chen-Guang Zhang, Bao-Jia Cai and Hai-Dong Lv
Funding Agency and Grant Number
Corresponding Author	Hai-Dong Lv, Professor, Department of Gastrointestinal Cancer Surgery, Qinghai Provincial People’s Hospital, No. 2 Gonghe Road, Chengdong District, Xining 810000, Qinghai Province, China. lvhaid@126.com
Key Words	Gastric cancer; Adverse reaction; Sintilimab; Oxaliplatin plus S-1 regimen; Programmed cell death protein 1
Core Tip	This real-world study systematically compared perioperative oxaliplatin plus S-1 combined with sintilimab, nab-paclitaxel plus oxaliplatin and S-1, and capecitabine plus oxaliplatin regimens in patients with advanced gastric cancer, focusing on treatment efficacy, survival outcomes, and safety. Beyond conventional survival analyses, a prognostic model was developed and validated to stratify progression-free survival risk using readily available clinicopathological and treatment response variables. The findings demonstrate that oxaliplatin plus S-1 combined with sintilimab is associated with favorable survival outcomes with manageable toxicity, and the proposed nomogram provides a practical tool for individualized risk assessment and treatment decision-making in perioperative advanced gastric cancer.
Citation	Zhou DX, Jiang SW, Zhang CG, Cai BJ, Lv HD. Perioperative SOX plus sintilimab vs P-SOX and CAPOX in advanced gastric cancer: A real-world comparison. World J Gastroenterol 2026; In press

Received	2026-02-06 01:56
Peer-Review Started	2026-02-06 01:57
First Decision by Editorial Office Director	2026-02-14 07:58
Return for Revision	2026-02-14 07:58
Revised	2026-02-25 05:56
Publication Fee Transferred	2026-02-26 07:43
Second Decision by Editor	2026-03-27 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-27 08:39
Articles in Press	2026-03-27 08:39
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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