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Publication Name World Journal of Psychiatry
Manuscript ID 119817
Country China
Category Psychiatry
Manuscript Type Retrospective Study
Article Title Effect of esketamine-assisted regional block on post-traumatic stress disorder after radical lung cancer surgery: A retrospective clinical study
Manuscript Source Unsolicited Manuscript
All Author List Yan-Lin Chen, Teng-Chen Feng, Xiao-Min Zhang, Na Liu, Hui-Min Yuan, Rui Bian, Jie Yao and Zhen Xing
Funding Agency and Grant Number
Funding Agency Grant Number
2024 Hebei Provincial Medical Science Research Project 20241120
Corresponding Author Zhen Xing, Department of Anesthesiology, The First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Zhangjiakou 075000, Hebei Province, China. 13011560235@163.com
Key Words Post-traumatic stress disorder; Esketamine; Thoracic surgery; Regional nerve block; Postoperative recovery; Inflammation; Pain management
Core Tip Post-traumatic stress disorder (PTSD) is a real complication impeding recovery and quality of life in patients undergoing radical lung cancer surgery. This study shows that esketamine-assisted regional block can significantly reduce the incidence of postoperative PTSD through inhibition of stress and inflammatory response. These findings suggest that refining perioperative anesthetic techniques, improving postoperative pain treatment and tracking inflammatory indicators are of clinical relevance in early PTSD prevention and will provide novel reference data for comprehensive interventions in lung cancer patients.
Citation

Chen YL, Feng TC, Zhang XM, Liu N, Yuan HM, Bian R, Yao J, Xing Z. Effect of esketamine-assisted regional block on post-traumatic stress disorder after radical lung cancer surgery: A retrospective clinical study. World J Psychiatry 2026; 16(6): 119817

Received
2026-03-10 10:12
Peer-Review Started
2026-03-10 10:12
First Decision by Editorial Office Director
2026-04-02 05:59
Return for Revision
2026-04-02 05:59
Revised
2026-04-27 12:24
Publication Fee Transferred
2026-04-30 04:12
Second Decision by Editor
2026-05-20 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-20 06:57
Articles in Press
2026-05-20 06:57
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-20 09:50
ISSN 2220-3206 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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