Publication Name	World Journal of Psychiatry
Manuscript ID	119855
Country	China

Category	Clinical Neurology
Manuscript Type	Correspondence
Article Title	Letter to the Editor: From prototype to paradigm - a paradigm shift in multimodal detection of adolescent depression
Manuscript Source	Invited Manuscript
All Author List	Meng-Yang He and Xin-Yue Li
Funding Agency and Grant Number	Funding Agency Grant Number Joint Project of Hubei Provincial Natural Science Foundation No. 2025AFD654
Corresponding Author	Meng-Yang He, Assistant Professor, Department of Psychology, Wuhan Sports University, No. 461 Luoyu Road, Zhuodaoquan Street, Hongshan District, Wuhan 430079, Hubei Province, China. 2021008@whsu.edu.cn
Key Words	Adolescent depression; Prototype refinement; Multi-center collaboration; Multimodal detection; Clinical application challenges
Core Tip	This commentary highlights Zeng et al’s multimodal adolescent depression detection approach (facial/vocal signals + Chinese Secondary School Students Depression Scale), which outperforms traditional methods via extreme gradient boosting. It notes the prototype’s regional/experimental limitations, advocates integrating neurophysiological signals and wearable data, and calls for interdisciplinary, multi-center collaboration to advance it to a clinical paradigm.
Citation	He MY, Li XY. Letter to the Editor: From prototype to paradigm - a paradigm shift in multimodal detection of adolescent depression. World J Psychiatry 2026; In press

Received	2026-02-09 01:22
Peer-Review Started	2026-02-09 01:23
First Decision by Editorial Office Director	2026-02-12 07:51
Return for Revision	2026-02-12 07:51
Revised	2026-02-21 15:31
Publication Fee Transferred
Second Decision by Editor	2026-05-20 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-20 06:40
Articles in Press	2026-05-20 06:40
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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