Publication Name	World Journal of Diabetes
Manuscript ID	119913
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Prospective Study
Article Title	Visit-to-visit variability of creatinine levels associated with progression of proteinuria in Chinese patients with type 2 diabetes mellitus
Manuscript Source	Unsolicited Manuscript
All Author List	Yu-Hang Ma, Xiao-Hui Wei, Yue Liu, Li-Ping Gu, Ting-Ting Shen, Ting-Ting Fan, Qin Qin, Ai-Fang Zhang, Rui-Ping Wang and Yu-Fan Wang
Funding Agency and Grant Number	Funding Agency Grant Number Noncommunicable Chronic Diseases-National Science and Technology Major Project No. 2023ZD0508104 Shanghai Science and Technology Commission Foundation No. 23ZR1451500 National Health Commission Medical Health Science and Technology Development Research Center “Innovative Medicine Post-Marketing Clinical Research Project” No. WKZX2023CX150002 Fourth Round of “Committee and Hospital Cooperation” (Shanghai Songjiang District Health Commission and Shanghai General People’s Hospital) Joint Research Project and the Chronic Disease Management Research Project of National Health Commission Capacity Building and Continuing Education Center No. GWJJMB202510024038
Corresponding Author	Yu-Fan Wang, MD, Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai 200080, China. yyffwang@sina.com
Key Words	Metabolic parameters; Creatinine; Proteinuria; Progression; Type 2 diabetes mellitus
Core Tip	This was a prospective cohort study to comprehensively analyze the relationship between variability of metabolic parameters and proteinuria in type 2 diabetes mellitus (T2DM). Variability in creatinine levels during follow-up was an independent risk factor for the progression of proteinuria, and this finding was consistent across patients stratified by different baseline urinary albumin-to-creatinine ratio. These results offer a reference for incorporating dynamic creatinine variability into proteinuria risk monitoring strategies in T2DM patients.
Citation	Ma YH, Wei XH, Liu Y, Gu LP, Shen TT, Fan TT, Qin Q, Zhang AF, Wang RP, Wang YF. Visit-to-visit variability of creatinine levels associated with progression of proteinuria in Chinese patients with type 2 diabetes mellitus. World J Diabetes 2026; In press

Received	2026-02-10 00:35
Peer-Review Started	2026-02-11 08:57
First Decision by Editorial Office Director	2026-02-26 07:21
Return for Revision	2026-02-26 07:21
Revised	2026-03-12 02:07
Publication Fee Transferred	2026-03-13 12:46
Second Decision by Editor	2026-04-02 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-10 06:01
Articles in Press	2026-04-10 06:01
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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