Publication Name	World Journal of Clinical Cases
Manuscript ID	119927
Country	Saudi Arabia

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Extrapulmonary tuberculosis presenting with proximal oesophageal fistula and abdominal lymphadenopathy in a young man: A case report
Manuscript Source	Invited Manuscript
All Author List	Lama Mohamed, Ghassan Elsayed, Mohammed Kambal, Rami Soliman, Sufian Sirelkhatim and Eyad Gadour
Funding Agency and Grant Number
Corresponding Author	Eyad Gadour, CCST, Consultant, FACP, FRCP, MD, MRCP, Professor, Multiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Ammar Bin Thabit Street, Dammam 32253, Saudi Arabia. eyadgadour@doctors.org.uk
Key Words	Oesophageal tuberculosis; Oesophageal fistula; Pancreatic tuberculosis; Abdominal lymphadenopathy; Endoscopic ultrasound; Fine-needle aspiration; Paradoxical tuberculosis reaction; Case report
Core Tip	Extrapulmonary tuberculosis (TB) may present with atypical and misleading features that mimic malignancy. We report a young man from a TB-endemic region with persistent abdominal pain, dysphagia and weight loss after successful Helicobacter pylori eradication who was found to have a very short proximal oesophageal fistula, diffuse pancreatic enlargement and subdiaphragmatic lymphadenopathy. Endoscopic ultrasound (EUS)-guided fine-needle aspiration of abdominal lymph nodes revealed granulomatous inflammation highly suggestive of TB. Standard anti-TB therapy, extended to 12 months because of fistulating oesophageal disease and probable pancreatic involvement, led to complete clinical and radiological resolution, despite an interim paradoxical reaction. This case underscores the need to consider TB in patients presenting with unexplained oesophageal fistula and abdominal lymphadenopathy, and illustrates the pivotal diagnostic role of EUS-guided tissue sampling.
Citation	Mohamed L, Elsayed G, Kambal M, Soliman R, Sirelkhatim S, Gadour E. Extrapulmonary tuberculosis presenting with proximal oesophageal fistula and abdominal lymphadenopathy in a young man: A case report. World J Clin Cases 2026; In press

Received	2026-02-10 00:56
Peer-Review Started	2026-02-10 01:00
First Decision by Editorial Office Director	2026-02-25 07:55
Return for Revision	2026-02-25 07:55
Revised	2026-03-14 17:32
Publication Fee Transferred
Second Decision by Editor	2026-05-14 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-14 06:14
Articles in Press	2026-05-14 06:14
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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