Publication Name	World Journal of Biological Chemistry
Manuscript ID	119936
DOI	10.4331/wjbc.119936
Country	Japan

Category	Cell Biology
Manuscript Type	Minireviews
Article Title	Regenerative potential of von Hippel-Lindau tumor suppressor protein
Manuscript Source	Invited Manuscript
All Author List	Hiroshi Kanno and Kimihiro Nakahara
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Education, Culture, Sports, Science, and Technology of Japan No. 32713
Corresponding Author	Hiroshi Kanno, Academic Fellow, MD, PhD, Professor, Department of Neurosurgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. hiroshikannomd@nifty.com
Key Words	Regeneration; Von Hippel-Lindau; Mesenchymal stem cell; Neuronal disease; Hypoxia-inducible factor
Core Tip	The mechanism of action of von Hippel-Lindau (VHL) involved in neuronal differentiation is mediated through the inhibition of downstream signaling pathways, JAK-STAT, and HIF-VEGF pathways. In addition, because VHL promotes nerve regeneration, it is expected to be applied in neuronal regenerative medicine for traumatic brain injury and stroke.
Citation	Kanno H, Nakahara K. Regenerative potential of von Hippel-Lindau tumor suppressor protein. World J Biol Chem 2026; In press DOI: https://doi.org/10.4331/wjbc.119936
PDF	119936-in-press.pdf

Received	2026-02-11 01:03
Peer-Review Started	2026-02-11 01:04
First Decision by Editorial Office Director	2026-02-25 08:30
Return for Revision	2026-02-25 08:30
Revised	2026-03-11 07:30
Publication Fee Transferred
Second Decision by Editor	2026-06-17 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-17 07:13
Articles in Press	2026-06-17 07:13
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8454 (online)
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