Publication Name	World Journal of Gastroenterology
Manuscript ID	119939
Country	Egypt

Category	Gastroenterology & Hepatology
Manuscript Type	Correspondence
Article Title	Letter to the Editor: Artificial intelligence in hepatology - when deep learning meets drug-induced liver injury
Manuscript Source	Invited Manuscript
All Author List	Yasser Fouad, Alaa M Mostafa, Safaa M Abdelhalim and Mohammed Eslam
Funding Agency and Grant Number
Corresponding Author	Yasser Fouad, MD, Professor, Department of Endemic Medicine and Gastroenterology, Faculty of Medicine, Minia University, Main Road, Minia 19111, Egypt. yasserfouad10@yahoo.com
Key Words	Drug-induced liver injury; Pyrrolizidine alkaloid; Sinusoidal obstruction syndrome; Deep learning; Computed tomography model
Core Tip	Drug-induced liver injury remains challenging due to its vague presentation and reliance on exclusion-based techniques. This complexity is particularly evident in cases of pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome, which often require invasive treatments and expert imaging interpretation. Recent advancements in deep learning applied to computed tomography are changing the diagnostic landscape by identifying subtle, diffuse parenchymal abnormalities that might be missed using standard methods. Artificial intelligence can improve clinician performance, enhance diagnostic consistency, and reduce interpretation times, as demonstrated by the validated model discussed here. These integrated technologies could lead to more timely and informed clinical decision-making, improving the early identification of complex drug-induced liver injury characteristics.
Citation	Fouad Y, Mostafa AM, Abdelhalim SM, Eslam M. Letter to the Editor: Artificial intelligence in hepatology - when deep learning meets drug-induced liver injury. World J Gastroenterol 2026; In press

Received	2026-02-11 01:00
Peer-Review Started	2026-02-11 01:04
First Decision by Editorial Office Director	2026-03-20 10:57
Return for Revision	2026-03-20 10:57
Revised	2026-03-21 23:15
Publication Fee Transferred
Second Decision by Editor	2026-05-27 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-27 07:31
Articles in Press	2026-05-27 07:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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