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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 119966
Country China
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Cai Sheng and Huan Li
Funding Agency and Grant Number
Corresponding Author Huan Li, MD, Department of Oncology, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410000, Hunan Province, China. 15211450392@163.com
Key Words Sintilimab; Anlotinib; Hepatocellular carcinoma; Advanced unresectable disease; Progression-free survival
Core Tip This retrospective study demonstrates that the combination of sintilimab (an anti-programmed death receptor 1 antibody) and anlotinib (a multi-target anti-angiogenic TKI) significantly improves progression-free survival, overall survival, and tumor response rates compared to sintilimab monotherapy in patients with advanced unresectable hepatocellular carcinoma, with a manageable safety profile.
Citation Sheng C, Li H. Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma. World J Gastrointest Oncol 2026; In press
Received
2026-03-10 10:26
Peer-Review Started
2026-03-10 10:26
First Decision by Editorial Office Director
2026-03-20 10:02
Return for Revision
2026-03-20 10:02
Revised
2026-03-31 09:35
Publication Fee Transferred
Second Decision by Editor
2026-05-06 03:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-06 09:59
Articles in Press
2026-05-06 09:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com