Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	119971
Country	Mexico

Category	Oncology
Manuscript Type	Retrospective Cohort Study
Article Title	Factors associated with complete clinical response after neoadjuvant therapy in locally advanced rectal cancer: A Mexican retrospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Ismael Brito-Toledo, Jesús Alberto Sansón-Riofrío, Maria Teresa Cervantes-Díaz, Jazmín de Anda-González, Rafael Medrano-Guzmán, Emilio Moreno-González, Eduardo Vadillo and Antonio Ibarra
Funding Agency and Grant Number
Corresponding Author	Eduardo Vadillo, Oncololgy Research Unit, Mexican Institute for Social Security (IMSS), Av Cuauhtémoc No.330 Colonia Doctores. CP: 06720 Mexico City. Mexico., Mexico City 06720, Cuauhtémoc, Mexico. evadillo@hotmail.com
Key Words	Rectal neoplasms; Neoadjuvant therapy; Clinical complete response; Pathologic complete response; Watch-and-wait
Core Tip	Recognizing the high prevalence of locally advanced rectal cancer at presentation in the Mexican population, we assessed 101 patients with clinical stage II-III rectal cancer who underwent neoadjuvant therapy and found, consistent with global literature, that approximately 20% of patients achieved a complete response, while tumor size was inversely correlated with the probability of achieving a complete clinical response.
Citation	Brito-Toledo I, Sansón-Riofrío JA, Cervantes-Díaz MT, de Anda-González J, Medrano-Guzmán R, Moreno-González E, Vadillo E, Ibarra A. Factors associated with complete clinical response after neoadjuvant therapy in locally advanced rectal cancer: A Mexican retrospective study. World J Gastrointest Oncol 2026; In press

Received	2026-02-12 02:34
Peer-Review Started	2026-02-12 02:46
First Decision by Editorial Office Director	2026-02-25 03:10
Return for Revision	2026-02-25 03:10
Revised	2026-03-10 15:26
Publication Fee Transferred	2026-03-13 14:23
Second Decision by Editor	2026-03-26 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-26 06:37
Articles in Press	2026-03-26 06:37
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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